Penile cancer

A Thomas, A Necchi, A Muneer… - Nature Reviews …, 2021 - nature.com
Penile squamous cell carcinoma (PSCC) is a rare cancer with orphan disease designation
and a prevalence of 0.1–1 per 100,000 men in high-income countries, but it constitutes up to …

Management of advanced penile cancer

J Chahoud, M Kohli, PE Spiess - Mayo Clinic Proceedings, 2021 - Elsevier
Penile squamous cell carcinoma (PSCC) is a rare cancer, with approximately 2000 new
cases in the United States and 35,000 globally every year. Multiple risk factors are involved …

Safety and efficacy of immune checkpoint inhibitors in advanced penile cancer: report from the Global Society of Rare Genitourinary Tumors

T El Zarif, AH Nassar, GR Pond… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Treatment options for penile squamous cell carcinoma are limited. We sought to
investigate clinical outcomes and safety profiles of patients with penile squamous cell …

Assessment of PD-L1, TROP2, and nectin-4 expression in penile squamous cell carcinoma

B Tekin, JC Cheville, LH Hernandez, V Negron… - Human Pathology, 2023 - Elsevier
Objectives There is an unmet need for therapeutically relevant biomarkers for advanced
penile squamous cell carcinoma (pSCC). Proposed immunohistochemistry (IHC)-based …

Pembrolizumab for advanced penile cancer: a case series from a phase II basket trial

AW Hahn, J Chahoud, MT Campbell, DD Karp… - Investigational new …, 2021 - Springer
Background: Treatment options for unresectable, locally advanced or metastatic penile
squamous cell carcinoma (SCC) are limited. Previous studies have shown that 40–62% of …

Case report: two cases of chemotherapy refractory metastatic penile squamous cell carcinoma with extreme durable response to pembrolizumab

J Chahoud, WP Skelton IV, PE Spiess, C Walko… - Frontiers in …, 2020 - frontiersin.org
Background Penile squamous cell carcinoma (PSCC) is a rare malignancy, and those
patients with metastatic disease have limited treatment options. Treatment is largely …

A global approach to improving penile cancer care

M Bandini, M Ahmed, G Basile, N Watkin… - Nature reviews …, 2022 - nature.com
Rare tumours such as penile carcinoma have been largely neglected by the urology
scientific community in favour of more common—and, therefore, more easily fundable …

Recent advances in the management of penile cancer: a contemporary review of the literature

CE Stecca, M Alt, DM Jiang, P Chung, JM Crook… - Oncology and …, 2021 - Springer
Penile cancer is a rare condition, which mostly affects men in their sixth decade of life. The
most common histology is squamous cell carcinoma (SCC), with about half of the cases …

[HTML][HTML] Synergistic killing effects of PD-L1-CAR T cells and colorectal cancer stem cell-dendritic cell vaccine-sensitized T cells in ALDH1-positive colorectal cancer …

L Liu, Y Liu, Y **a, G Wang, X Zhang, H Zhang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are characterized by self-renewal and unlimited proliferation,
providing a basis for tumor occurrence, metastasis, and recurrence. Because CSCs are …

Current management and future perspectives of penile cancer: An updated review

F Peyraud, C Allenet, M Gross-Goupil… - Cancer Treatment …, 2020 - Elsevier
Penile cancer (PeCa) is a rare disease worldwide, accounting for less than one percent of
all malignancies in men. It usually presents as a painless ulcer or lump on the head of the …