T helper 2 cells in asthma
Allergic asthma is among the most common immune-mediated diseases across the world,
and type 2 immune responses are thought to be central to pathogenesis. The importance of …
and type 2 immune responses are thought to be central to pathogenesis. The importance of …
Understanding the development of Th2 cell-driven allergic airway disease in early life
B León - Frontiers in Allergy, 2023 - frontiersin.org
Allergic diseases, including atopic dermatitis, allergic rhinitis, asthma, and food allergy, are
caused by abnormal responses to relatively harmless foreign proteins called allergens …
caused by abnormal responses to relatively harmless foreign proteins called allergens …
Site-specific regulation of Th2 differentiation within lymph node microenvironments
MR Lyons-Cohen, EA Shamskhou… - Journal of Experimental …, 2024 - rupress.org
T helper 2 (Th2) responses protect against pathogens while also driving allergic
inflammation, yet how large-scale Th2 responses are generated in tissue context remains …
inflammation, yet how large-scale Th2 responses are generated in tissue context remains …
Irritable bowel syndrome: When food is a pain in the gut
H Hussein, S Van Remoortel… - Immunological …, 2024 - Wiley Online Library
Irritable bowel syndrome (IBS) is a chronic gastrointestinal condition associated with altered
bowel habits and recurrent abdominal pain, often triggered by food intake. Current …
bowel habits and recurrent abdominal pain, often triggered by food intake. Current …
The origins and longevity of IgE responses as indicated by serological and cellular studies in mice and humans
The existence of long‐lived IgE antibody‐secreting cells (ASC) is contentious, with the
maintenance of sensitization by the continuous differentiation of short‐lived IgE+ ASC a …
maintenance of sensitization by the continuous differentiation of short‐lived IgE+ ASC a …
[HTML][HTML] Prolonged T cell–DC macro-clustering within lymph node microenvironments initiates Th2 cell differentiation in a site-specific manner
MR Lyons-Cohen, EA Shamskhou, MY Gerner - bioRxiv, 2023 - ncbi.nlm.nih.gov
Formation of T helper 2 (Th2) responses has been attributed to low-grade T cell stimulation,
yet how large-scale polyclonal Th2 responses are generated in vivo remains unclear. Here …
yet how large-scale polyclonal Th2 responses are generated in vivo remains unclear. Here …
Protection acquired upon intraperitoneal group a Streptococcus immunization is independent of concurrent adaptive immune responses but relies on macrophages …
ABSTRACT Group A Streptococcus (GAS; Streptococcus pyogenes) is an important
bacterial pathogen causing over 700 million superficial infections and around 500.000 …
bacterial pathogen causing over 700 million superficial infections and around 500.000 …
How type‐2 dendritic cells induce Th2 differentiation: Instruction, repression, or fostering T cell‐T cell communication?
F Ronchese, GR Webb, S Ochiai, O Lamiable… - Allergy, 2025 - Wiley Online Library
Allergic disease is caused by the activation of allergen‐specific CD4+ type‐2 T follicular
helper cells (Tfh2) and T helper 2 (Th2) effector cells that secrete the cytokines IL‐4, IL‐5, IL …
helper cells (Tfh2) and T helper 2 (Th2) effector cells that secrete the cytokines IL‐4, IL‐5, IL …
IFN-I signaling in type 2 conventional dendritic cells supports TH2 and T follicular helper differentiation after allergen immunization
Type 2 dendritic cells (DC2s) are essential for TH2 differentiation, but the signaling
pathways involved in allergen sensing, DC activation and instruction of CD4+ T cell priming …
pathways involved in allergen sensing, DC activation and instruction of CD4+ T cell priming …
[PDF][PDF] An Investigation of Cytokine Signals Underlying CD4+ T-cell Differentiation and Expansion
GR Webb - 2023 - ourarchive.otago.ac.nz
In order to orchestrate immune responses to a wide variety of pathogenic stimuli, CD4+ T-
cells must integrate a variety of signals from conventional dendritic cells (cDCs), including …
cells must integrate a variety of signals from conventional dendritic cells (cDCs), including …