Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction

MJ Kreek, DA Nielsen, ER Butelman… - Nature neuroscience, 2005 - nature.com
Genetic variation may partially underlie complex personality and physiological traits—such
as impulsivity, risk taking and stress responsivity—as well as a substantial proportion of …

How can drug addiction help us understand obesity?

ND Volkow, RA Wise - Nature neuroscience, 2005 - nature.com
How can drug addiction help us understand obesity? | Nature Neuroscience Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Drug addiction

J Cami, M Farré - New England Journal of Medicine, 2003 - Mass Medical Soc
Drug Addiction | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective

A Alcaro, R Huber, J Panksepp - Brain research reviews, 2007 - Elsevier
The mesolimbic dopaminergic (ML-DA) system has been recognized for its central role in
motivated behaviors, various types of reward, and, more recently, in cognitive processes …

Neurobiology of addiction: An integrative review

A Goodman - Biochemical pharmacology, 2008 - Elsevier
Evidence that psychoactive substance use disorders, bulimia nervosa, pathological
gambling, and sexual addiction share an underlying biopsychological process is …

Specificity of genetic and environmental risk factors for symptoms of cannabis, cocaine, alcohol, caffeine, and nicotine dependence

KS Kendler, J Myers, CA Prescott - Archives of general psychiatry, 2007 - jamanetwork.com
Context Although genetic risk factors have been found to contribute to dependence on both
licit and illicit psychoactive substances, we know little of how these risk factors interrelate …

New insights into the genetics of addiction

MD Li, M Burmeister - Nature Reviews Genetics, 2009 - nature.com
Drug addiction is a common brain disorder that is extremely costly to the individual and to
society. Genetics contributes significantly to vulnerability to this disorder, but identification of …

Genes and (common) pathways underlying drug addiction

CY Li, X Mao, L Wei - PLoS computational biology, 2008 - journals.plos.org
Drug addiction is a serious worldwide problem with strong genetic and environmental
influences. Different technologies have revealed a variety of genes and pathways …

The common variants/multiple disease hypothesis of common complex genetic disorders

KG Becker - Medical hypotheses, 2004 - Elsevier
Unlike simple rare Mendelian disorders, the genetic basis for common disorders is unclear.
A general model of the genetics of common complex disorders is proposed which …

Genetic susceptibility to caffeine intake and metabolism: a systematic review

JJL Low, BJW Tan, LX Yi, ZD Zhou, EK Tan - Journal of Translational …, 2024 - Springer
Background Coffee and tea consumption account for most caffeine intake and 2–3 billion
cups are taken daily around the world. Caffeine dependence is a widespread but under …