Bakuchiol–a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
TPA Krishna, B Edachery, S Athalathil - RSC advances, 2022 - pubs.rsc.org
Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea
corylifolia. It has been reported to possess a broad range of biological and pharmacological …
corylifolia. It has been reported to possess a broad range of biological and pharmacological …
Deploying microbial synthesis for halogenating and diversifying medicinal alkaloid scaffolds
Plants produce some of the most potent therapeutics and have been used for thousands of
years to treat human diseases. Today, many medicinal natural products are still extracted …
years to treat human diseases. Today, many medicinal natural products are still extracted …
Synthesis and Evaluation of Bakuchiol Derivatives as Potent Anti-inflammatory Agents in Vitro and in Vivo
Q Ma, M Bian, G Gong, C Bai, C Liu, C Wei… - Journal of Natural …, 2022 - ACS Publications
Bakuchiol, a prenylated phenolic monoterpene derived from the fruit of Psoralen corylifolia
L.(Buguzhi), is widely used to treat tumors, viruses, inflammation, and bacterial infections. In …
L.(Buguzhi), is widely used to treat tumors, viruses, inflammation, and bacterial infections. In …
Chemical Predictive Modelling and Natural Product‐based Divergent Synthesis–Design of Type B PPAPs with Nanomolar Activities against MRSA
P Peslalz, A Vorbach, A Bleisch… - … A European Journal, 2024 - Wiley Online Library
In response to the pressing global challenge of antibiotic resistance, time efficient design
and synthesis of novel antibiotics are of immense need. Polycyclic polyprenylated …
and synthesis of novel antibiotics are of immense need. Polycyclic polyprenylated …
Synthesis and biological studies of (+)-liquiditerpenoic acid A (abietopinoic acid) and representative analogues: SAR studies
D Hamulic, M Stadler, S Hering… - Journal of natural …, 2019 - ACS Publications
The first semisynthesis and biological profiling of the new abietane diterpenoid (+)-
liquiditerpenoic acid A (abietopinoic acid)(7) along with several analogues are reported. The …
liquiditerpenoic acid A (abietopinoic acid)(7) along with several analogues are reported. The …
Recent advances in the chemistry and biology of bakuchiol and its derivatives: An updated review
Bakuchiol is a meroterpene natural product distributed in various plants. It possesses
several biological activities particularly anticancer. A large number of analogs have been …
several biological activities particularly anticancer. A large number of analogs have been …
Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells
Ethnopharmacological relevance The past few years have witnessed an increasing interest
in essential oils (EOs) as potential therapeutic agents against a wide variety of pathologies …
in essential oils (EOs) as potential therapeutic agents against a wide variety of pathologies …
Synthesis and anti-proliferative evaluation of novel 3, 4-dihydro-2 H-1, 3-oxazine derivatives of bakuchiol
A new series of 3, 4-dihydro-2H-1, 3-oxazine derivatives of bakuchiol 1 was synthesized
through the Mannich-type condensation–cyclization reaction of 1 with formaldehyde and …
through the Mannich-type condensation–cyclization reaction of 1 with formaldehyde and …
Bakuchiol targets mitochondrial proteins, prohibitins and voltage-dependent anion channels: New insights into develo** antiviral agents
M Shoji, T Esumi, T Masuda, N Tanaka… - Journal of Biological …, 2024 - ASBMB
We previously reported that bakuchiol, a phenolic isoprenoid anticancer compound, and its
analogs exert anti-influenza activity. However, the proteins targeted by bakuchiol remain …
analogs exert anti-influenza activity. However, the proteins targeted by bakuchiol remain …
Bakuchiol: A potential anticancer compound from Psoralea corylifolia linn
Background: Bakuchiol is a monoterpene phenol isolated from the seeds of Psoralea
corylifolia Linn. It is used traditionally in Indian and Chinese medicine and has been …
corylifolia Linn. It is used traditionally in Indian and Chinese medicine and has been …