Memory engrams: Recalling the past and imagining the future
BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …
Forgetting as a form of adaptive engram cell plasticity
One leading hypothesis suggests that memories are stored in ensembles of neurons (or
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …
Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory
Tremendous strides have been made in our understanding of the neurobiological substrates
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …
Neuromodulated spike-timing-dependent plasticity, and theory of three-factor learning rules
Classical Hebbian learning puts the emphasis on joint pre-and postsynaptic activity, but
neglects the potential role of neuromodulators. Since neuromodulators convey information …
neglects the potential role of neuromodulators. Since neuromodulators convey information …
The brain in motion: How ensemble fluidity drives memory-updating and flexibility
While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …
simply conserve veridical representations of the past but must continually integrate new …
Annual Research Review: Rethinking childhood trauma‐new research directions for measurement, study design and analytical strategies
A Danese - Journal of child psychology and psychiatry, 2020 - Wiley Online Library
Childhood trauma is a key modifiable risk factor for psychopathology. Despite significant
scientific advances, traumatised children still have poorer long‐term outcomes than …
scientific advances, traumatised children still have poorer long‐term outcomes than …
Spike timing-dependent plasticity and memory
Spike timing-dependent plasticity (STDP) is a bidirectional form of synaptic plasticity
discovered about 30 years ago and based on the relative timing of pre-and post-synaptic …
discovered about 30 years ago and based on the relative timing of pre-and post-synaptic …
[HTML][HTML] Examining the engram encoding specificity hypothesis in mice
According to the encoding specificity hypothesis, memory is best recalled by retrieval cues
that overlap with training cues. Human studies generally support this hypothesis. However …
that overlap with training cues. Human studies generally support this hypothesis. However …
Examining memory linking and generalization using scFLARE2, a temporally precise neuronal activity tagging system
How memories are organized in the brain influences whether they are remembered
discretely versus linked with other experiences or whether generalized information is …
discretely versus linked with other experiences or whether generalized information is …
Psychometry: An omnifit model for image reconstruction from human brain activity
Reconstructing the viewed images from human brain activity bridges human and computer
vision through the Brain-Computer Interface. The inherent variability in brain function …
vision through the Brain-Computer Interface. The inherent variability in brain function …