Systematic review of Mendelian randomization studies on risk of cancer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …
(MR) literature on cancer risk and to identify associations supported by robust evidence …
Linking physical activity to breast cancer via sex steroid hormones, part 2: the effect of sex steroid hormones on breast cancer risk
We undertook a systematic review and appraised the evidence for an effect of circulating sex
steroid hormones and sex hormone–binding globulin (SHBG) on breast cancer risk in pre …
steroid hormones and sex hormone–binding globulin (SHBG) on breast cancer risk in pre …
Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study
Background Breast cancer (BC) has the highest cancer incidence and mortality in women
worldwide. Observational epidemiological studies suggest a positive association between …
worldwide. Observational epidemiological studies suggest a positive association between …
Identifying and ranking causal biochemical biomarkers for breast cancer: a Mendelian randomisation study
Background Only a few of the 34 biochemical biomarkers measured in the UK Biobank
(UKB) have been associated with breast cancer, with many associations suffering from …
(UKB) have been associated with breast cancer, with many associations suffering from …
Mendelian randomization analyses of 23 known and suspected risk factors and biomarkers for breast cancer overall and by molecular subtypes
Many risk factors have been identified for breast cancer. The potential causality for some of
them remains uncertain, and few studies have comprehensively investigated these …
them remains uncertain, and few studies have comprehensively investigated these …
Endogenous hormones and risk of invasive breast cancer in pre-and post-menopausal women: findings from the UK Biobank
S Tin Tin, GK Reeves, TJ Key - British journal of cancer, 2021 - nature.com
Background Some endogenous hormones have been associated with breast cancer risk,
but the nature of these relationships is not fully understood. Methods UK Biobank was used …
but the nature of these relationships is not fully understood. Methods UK Biobank was used …
A bidirectional Mendelian randomized study of classical blood lipids and venous thrombosis
L Lin, P Luo, M Yang, J Wang, W Hou, P Xu - Scientific Reports, 2023 - nature.com
There is still some controversy about the relationship between lipids and venous thrombosis
(VTE). A bidirectional Mendelian randomization (MR) study was conducted to clarify the …
(VTE). A bidirectional Mendelian randomization (MR) study was conducted to clarify the …
[HTML][HTML] Combination of the biomarkers for aging and cancer?-Challenges and current status
D Li, F Ju, H Wang, C Fan, JC Jacob, S Gul… - Translational …, 2023 - Elsevier
The proportion of patients diagnosed with cancer has been shown to rise with the increasing
aging global population. Advanced age is a major risk factor for morbidity and mortality in …
aging global population. Advanced age is a major risk factor for morbidity and mortality in …
Crown-like structures in breast adipose tissue: early evidence and current issues in breast cancer
Simple Summary Obesity increases the risk of postmenopausal, hormone receptor-positive
breast cancer and has been linked to a higher risk of recurrence and mortality. During …
breast cancer and has been linked to a higher risk of recurrence and mortality. During …
Sex-specific associations of sex hormone binding globulin with CKD and kidney function: a univariable and multivariable mendelian randomization study in the UK …
Background Kidney function declines faster in men. Testosterone levels may mediate the
sex disparity. Correspondingly, levels of sex hormone binding globulin (SHBG), which …
sex disparity. Correspondingly, levels of sex hormone binding globulin (SHBG), which …