Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Heterostructural Nanoadjuvant CuSe/CoSe2 for Potentiating Ferroptosis and Photoimmunotherapy through Intratumoral Blocked Lactate Efflux

C Yang, M Wang, M Chang, M Yuan… - Journal of the …, 2023 - ACS Publications
The desirable curative effect in clinical immunotherapy has been challenging due to the
immunosuppressive tumor microenvironment (TME) with high lactic acid (LA) metabolism in …

Metal-organic framework nanoagent induces cuproptosis for effective immunotherapy of malignant glioblastoma

QX Huang, JL Liang, QW Chen, XK **, MT Niu… - Nano Today, 2023 - Elsevier
Glioblastoma (GBM) is an aggressive brain cancer with an immunosuppressive tumor
microenvironment. Here, a copper-based nanoplatform BSO-CAT@ MOF-199@ DDM …

Ferroptosis nanomedicine: clinical challenges and opportunities for modulating tumor metabolic and immunological landscape

H Yang, X Yao, Y Liu, X Shen, M Li, Z Luo - Acs Nano, 2023 - ACS Publications
Ferroptosis, a type of regulated cell death driven by iron-dependent phospholipid
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …

Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics

S Roy, N Bag, S Bardhan, I Hasan, B Guo - Advanced drug delivery reviews, 2023 - Elsevier
Fluorescence imaging in the second near-infrared window (NIR-II) has become a prevalent
choice owing to its appealing advantages like deep penetration depth, low …

Hybrid nanomaterials for cancer immunotherapy

J Li, W Lu, Y Yang, R **ang, Y Ling, C Yu… - Advanced …, 2023 - Wiley Online Library
Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

Metal–phenolic network composites: from fundamentals to applications

Z Lin, H Liu, JJ Richardson, W Xu, J Chen… - Chemical Society …, 2024 - pubs.rsc.org
Composites with tailored compositions and functions have attracted widespread scientific
and industrial interest. Metal–phenolic networks (MPNs), which are composed of phenolic …

Self-driven nanoprodrug platform with enhanced ferroptosis for synergistic photothermal-IDO immunotherapy

P Huang, Y Yang, W Wang, Z Li, N Gao, H Chen… - Biomaterials, 2023 - Elsevier
Insufficient immune stimulation and stubborn immune resistance are the critical factors
limiting tumor immunotherapy. Here, we report a multifunctional nanoprodrug platform with …

Ferroptosis: a double-edged sword mediating immune tolerance of cancer

Q Dang, Z Sun, Y Wang, L Wang, Z Liu, X Han - Cell death & disease, 2022 - nature.com
The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …