Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

In the adult rodent brain, neural stem cells (NSCs) persist in the ventricular-subventricular
zone (V-SVZ) and the subgranular zone (SGZ), which are specialized niches in which young …

Endothelial cells that line capillaries are not just passive conduits for delivering blood.
Tissue-specific endothelium establishes specialized vascular niches that deploy sets of …

A large population of neural stem/precursor cells (NSCs) persists in the ventricular–
subventricular zone (V-SVZ) located in the walls of the lateral brain ventricles. V-SVZ NSCs …

Multiciliated cells are epithelial cells that are in contact with bodily fluids and are required for
the proper function of major organs including the brain, the respiratory system and the …

The gut and liver are recognized to mutually communicate through the biliary tract, portal
vein, and systemic circulation. However, it remains unclear how this gut-liver axis regulates …

Sphere-forming assays have been widely used to retrospectively identify stem cells based
on their reported capacity to evaluate self-renewal and differentiation at the single-cell level …

The Notch pathway is often regarded as a developmental pathway, but components of Notch
signalling are expressed and active in the adult brain. With the advent of more sophisticated …

Major developments in the neural stem cell (NSC) field in recent years provide new insights
into the nature of the NSC niche. In this perspective, we integrate recent anatomical data on …

The vasculature is a prominent component of the subventricular zone neural stem cell niche.
Although quiescent neural stem cells physically contact blood vessels at specialized …