Mechanochemistry: new tools to navigate the uncharted territory of “impossible” reactions

F Cuccu, L De Luca, F Delogu, E Colacino… - …, 2022 - Wiley Online Library
Mechanochemical transformations have made chemists enter unknown territories, forcing a
different chemistry perspective. While questioning or revisiting familiar concepts belonging …

Continuous‐flow technology—a tool for the safe manufacturing of active pharmaceutical ingredients

B Gutmann, D Cantillo… - Angewandte Chemie …, 2015 - Wiley Online Library
In the past few years, continuous‐flow reactors with channel dimensions in the micro‐or
millimeter region have found widespread application in organic synthesis. The characteristic …

Recent advances in the transition metal catalyzed carbonylation of alkynes, arenes and aryl halides using CO surrogates

P Gautam, BM Bhanage - Catalysis Science & Technology, 2015 - pubs.rsc.org
Transition metal catalyzed carbonylation reactions using carbon monoxide as the C-1
source have occupied an all important position in catalysis which is subsequently related to …

Photoinduced copper-catalyzed radical aminocarbonylation of cycloketone oxime esters

B Lu, Y Cheng, LY Chen, JR Chen, WJ ** CO gas-free
carbonylation reactions and the application of carbonylation reactions in the synthesis of …

Chloroform as a Carbon Monoxide Precursor: In or Ex Situ Generation of CO for Pd-Catalyzed Aminocarbonylations

SN Gockel, KL Hull - Organic letters, 2015 - ACS Publications
Conditions for the rapid hydrolysis of chloroform to carbon monoxide (CO) using
heterogeneous CsOH· H2O are described. CO and 13CO can be generated cleanly and …

State-of-the-art palladium-catalyzed alkoxycarbonylations

R Sang, Y Hu, R Razzaq, R Jackstell… - Organic Chemistry …, 2021 - pubs.rsc.org
Palladium-catalyzed alkoxycarbonylation reactions allow for the efficient conversion of
widely available unsaturated compounds, CO and alcohols into the corresponding …

Transition-metal-catalyzed transfer carbonylation with HCOOH or HCHO as non-gaseous C1 source

J Cao, ZJ Zheng, Z Xu, LW Xu - Coordination Chemistry Reviews, 2017 - Elsevier
While carbon monoxide (CO) gas has been extensively applied in the bulk chemical
industry, its intrinsic properties such as high toxicity, flammability, and special equipment …

Palladium-catalyzed selective generation of CO from formic acid for carbonylation of alkenes

R Sang, P Kucmierczyk, K Dong, R Franke… - Journal of the …, 2018 - ACS Publications
A general and selective palladium-catalyzed alkoxycarbonylation of all kinds of alkenes with
formic acid (HCOOH, FA) is described. Terminal, di-, tri-, and tetra-substituted including …