Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

Tuberculosis (TB) is the most common cause of death from infectious disease worldwide. A
substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG …

Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Aminoacyl-tRNA synthetases (ARSs) play a vital role in protein synthesis by linking amino
acids to their cognate transfer RNAs (tRNAs). This typical function has been well recognized …

Tuberculosis (TB) treatment monitoring is paramount to clinical decision-making and the
host biomarkers appears to play a significant role. The currently available diagnostic …

Lung inflammation indicated by 18F-labeled fluorodeoxyglucose (FDG) in patients with
tuberculosis is associated with disease severity and relapse risk upon treatment completion …

The tuberculosis (TB) vaccine Bacillus Calmette‐Guérin (BCG) was introduced 100 years
ago, but as it provides insufficient protection against TB disease, especially in adults, new …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Highlights•Review covering application of metabolomics and lipidomics throughout the drug
discovery and development process.•Focus on basic research, target identification …

Tuberculosis (TB) is the leading cause of death among infectious diseases, and the ratio of
cases in which its pathogen Mycobacterium tuberculosis (Mtb) is drug resistant has been …