The organs and metabolic pathways involved in energy metabolism, and the process of ATP
production from nutrients, are comparable between humans and Drosophila melanogaster …

The deposition of storage fat in the form of triacylglycerol (TAG) is an evolutionarily
conserved strategy to cope with fluctuations in energy availability and metabolic stress …

Several studies have been published introducing Drosophila melanogaster as a research
model to investigate the effects of high-calorie diets on metabolic dysfunctions. However …

Aedes aegypti female mosquitoes require vertebrate blood for their egg production and
consequently they become vectors of devastating human diseases. Amino acids (AAs) and …

Sex differences in whole-body fat storage exist in many species. For example, Drosophila
females store more fat than males. Yet, the mechanisms underlying this sex difference in fat …

Overweight and obesity are health conditions tightly related to a number of metabolic
complications collectively called “metabolic syndrome”(MetS). Clinical diagnosis of MetS …

Background The adaptive significance of phenotypic changes elicited by environmental
conditions experienced early in life has long attracted attention in evolutionary biology. In …

How lifespan and body weight vary as a function of diet and genetic differences is not well
understood. Here we quantify the impact of differences in diet on lifespan in a genetically …

The prevalence of obesity is increasing in older adults and contributes to age-related
decline. Caloric restriction (CR) alleviates obesity phenotypes and delays the onset of age …

Inflammatory bowel diseases (IBDs) are characterized by chronic relapsing intestinal
inflammation that causes digestive system dysfunction. For years, researchers have been …