[HTML][HTML] Genetic background in nonalcoholic fatty liver disease: a comprehensive review

FS Macaluso, M Maida, S Petta - World Journal of …, 2015 - ncbi.nlm.nih.gov
In the Western world, nonalcoholic fatty liver disease (NAFLD) is considered as one of the
most significant liver diseases of the twenty-first century. Its development is certainly driven …

Genetics of pediatric obesity

M Manco, B Dallapiccola - Pediatrics, 2012 - publications.aap.org
Onset of obesity has been anticipated at earlier ages, and prevalence has dramatically
increased worldwide over the past decades. Epidemic obesity is mainly attributable to …

Low body mass index in endometriosis is promoted by hepatic metabolic gene dysregulation in mice

TG Goetz, R Mamillapalli, HS Taylor - Biology of reproduction, 2016 - academic.oup.com
The gynecological disease endometriosis is characterized by the deposition and
proliferation of endometrial cells outside the uterus and clinically is linked to low body mass …

[HTML][HTML] Physical activity and obese children

AM McManus, RR Mellecker - Journal of Sport and Health Science, 2012 - Elsevier
Childhood obesity is an epidemic of global proportions, accompanied by an alarming
increase in various metabolic disorders. It would appear that childhood obesity stems largely …

Dissecting miRNA–gene networks to map clinical utility roads of pharmacogenomics-guided therapeutic decisions in cardiovascular precision medicine

F Chatzopoulou, KA Kyritsis, CI Papagiannopoulos… - Cells, 2022 - mdpi.com
MicroRNAs (miRNAs) create systems networks and gene-expression circuits through
molecular signaling and cell interactions that contribute to health imbalance and the …

The influence of the differentiation of genes encoding peroxisome proliferator-activated receptors and their coactivators on nutrient and energy metabolism

A Maciejewska-Skrendo, M Massidda, F Tocco… - Nutrients, 2022 - mdpi.com
Genetic components may play an important role in the regulation of nutrient and energy
metabolism. In the presence of specific genetic variants, metabolic dysregulation may occur …

The fatty acid species and quantity consumed by the breastfed infant are important for growth and development

AD George, MCL Gay, ME Wlodek, K Murray… - Nutrients, 2021 - mdpi.com
The fatty acids (FAs) of human milk (HM) are the building blocks of the HM lipidome,
contributing to infant health and development; however, this has not been comprehensively …

PPARγ2Pro12Ala Polymorphism and Human Health

W He - PPAR research, 2009 - Wiley Online Library
The nuclear hormone receptor peroxisome proliferator activated receptor gamma (PPARγ) is
an important transcription factor regulating adipocyte differentiation, lipid and glucose …

[HTML][HTML] A common variant in the peroxisome proliferator–activated receptor-γ coactivator-1α gene is associated with nonalcoholic fatty liver disease in obese children

YC Lin, PF Chang, MH Chang, YH Ni - The American journal of clinical …, 2013 - Elsevier
Background: The single nucleotide polymorphism in the peroxisome proliferator–activated
receptor-γ coactivator (PGC)-1α gene (PPARGC1A) was identified to be associated with …

Obesity and eating behaviour in children and adolescents: contribution of common gene polymorphisms

J Cecil, M Dalton, G Finlayson, J Blundell… - … Review of Psychiatry, 2012 - Taylor & Francis
The prevalence of childhood obesity is increasing in many countries and confers risks for
early type 2 diabetes, cardiovascular disease and metabolic syndrome. In the presence of …