Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …

Autophagic pathways cross with lipid homeostasis and thus provide energy and essential
building blocks that are indispensable for liver functions. Energy deficiencies are …

BACKGROUND The defining feature of eukaryotic cells is the presence of membrane-bound
organelles of diverse kinds, each with specialized functions. Most organelles have multiple …

Lipid droplets are dynamic organelles that store neutral lipids during times of energy excess
and serve as an energy reservoir during deprivation. Many prevalent metabolic diseases …

Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …

Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

TMEM41B and VMP1 are integral membrane proteins of the endoplasmic reticulum (ER)
and regulate the formation of autophagosomes, lipid droplets (LDs), and lipoproteins …

Saccharomyces cerevisiae is an efficient host for natural-compound production and
preferentially employed in academic studies and bioindustries. However, S. cerevisiae …

How proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood.
Using Drosophila and human cells, we show here that seipin, an ER protein implicated in …