SUMMARY Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large
Parvoviridae family, are human pathogens responsible for a variety of diseases. For B19V in …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

Bone marrow transplantation is the primary therapy for numerous hematopoietic disorders.
The efficiency of bone marrow transplantation depends on the function of long-term …

Although O2 concentrations are considerably lowered in vivo, depending on the tissue and
cell population in question (some cells need almost anoxic environment for their …

Rat mesenchymal stem cells (rMSCs) represent a small portion of the cells in the stromal
compartment of bone marrow and have the potential to differentiate into bone, cartilage, fat …

Hypoxia is known to act as a general stimulator of cells derived from marrow precursors. We
investigated the effect of oxygen tension on the formation and function of osteoclasts, the …

Bone homeostasis is profoundly affected by local pH and oxygen tension. It has long been
recognised that the skeleton contains a large reserve of alkaline mineral (hydroxyapatite) …

Hematopoietic cells of various lineages are organized in distinct cellular architectures in the
bone marrow hematopoietic compartment (BMHC). The homogeneous Kroghian model …

Stem cells have emerged as the starting material of choice for bioprocesses to produce cells
and tissues to treat degenerative, genetic, and immunological disease. Translating the …

Human bone marrow (BM) is a tissue of complex architectural organization, which includes
granulopoietic loci, erythroblastic islets, and lymphocytic nodules. Oxygen tension (pO 2) is …