Objectives: In this cross-sectional study, we tested the construct validity of a “total SVD
score,” which combines individual MRI features of small-vessel disease (SVD) in one …

Up to 12% of patients with stroke have intracranial arterial dolichoectasia (IADE) and the
basilar artery is affected in 80% of these cases. Diagnostic criteria and prognosis studies of …

Dolichoectasia (dilatative arteriopathy) describes marked elongation, widening, and
tortuosity of arteries. The intracranial vertebral and basilar arteries are preferentially …

Objective: The long-term prognosis of patients with vertebrobasilar dolichoectasia (VBD) is
unknown. The purpose of this study was to explore the natural history of VBD, evaluate its …

Dolichoectasia is an arterial disease that causes dilatation and/or tortuosity of the affected
vessel. The prevalence of dolichoectasia increases with age, and this disease is also …

Murine chronic cerebral hypoperfusion (CCH) results in white matter (WM) injury and
behavioral deficits. Pericytes influence blood–brain barrier (BBB) integrity and cerebral …

An increased diameter (ectasis) and/or long and tortuous course (dolichosis) of at least one
cerebral artery define intracranial arterial dolichoectasia (IADE). IADE could be detected …

Background: Clinicoradiological variability of vertebrobasilar dolichoectasia (VBD) is known.
Little is known about cardiovascular disease (CVD) risk and neuroradiological profiles of …

Background and Purpose—Intracranial arterial dolichoectasia (IADE) is a poorly understood
arteriopathy compared with intracranial atherosclerotic stenosis (ICAS). We aimed to …

Background and purpose Late‐onset Pompe disease (LOPD) is a rare, multisystem disorder
that is well established to mainly impair skeletal muscle function. Systematic studies …