Cannabinoid receptors and the endocannabinoid system: signaling and function in the central nervous system

S Zou, U Kumar - International journal of molecular sciences, 2018 - mdpi.com
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant
Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …

Cannabis use and cannabis use disorder

JP Connor, D Stjepanović, B Le Foll, E Hoch… - Nature Reviews …, 2021 - nature.com
Cannabis use disorder (CUD) is an underappreciated risk of using cannabis that affects~
10% of the 193 million cannabis users worldwide. The individual and public health burdens …

Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning

G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

An introduction to the endogenous cannabinoid system

HC Lu, K Mackie - Biological psychiatry, 2016 - Elsevier
The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays
important roles in central nervous system development, synaptic plasticity, and the response …

A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex

H Taniguchi, M He, P Wu, S Kim, R Paik, K Sugino… - Neuron, 2011 - cell.com
A key obstacle to understanding neural circuits in the cerebral cortex is that of unraveling the
diversity of GABAergic interneurons. This diversity poses general questions for neural circuit …

Stress, memory and the amygdala

B Roozendaal, BS McEwen, S Chattarji - Nature Reviews …, 2009 - nature.com
Emotionally significant experiences tend to be well remembered, and the amygdala has a
pivotal role in this process. But the efficient encoding of emotional memories can become …

Endocannabinoid signaling and synaptic function

PE Castillo, TJ Younts, AE Chávez, Y Hashimotodani - Neuron, 2012 - cell.com
Endocannabinoids are key modulators of synaptic function. By activating cannabinoid
receptors expressed in the central nervous system, these lipid messengers can regulate …

Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations

T Klausberger, P Somogyi - Science, 2008 - science.org
In the cerebral cortex, diverse types of neurons form intricate circuits and cooperate in time
for the processing and storage of information. Recent advances reveal a spatiotemporal …

The molecular logic of endocannabinoid signalling

D Piomelli - Nature Reviews Neuroscience, 2003 - nature.com
The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …