We conducted a systematic review of the literature on the effects of cordycepin on cell
survival and proliferation, inflammation, signal transduction and animal models. A total of …

Cordycepin (3′-deoxyadenosine), a cytotoxic nucleoside analogue found in Cordyceps
militaris, has attracted much attention due to its therapeutic potential and biological value …

Background: Recent reports suggested the involvement of oxidative stress-and endoplasmic
reticulum stress (ERS)-associated pathways in the progression of ischemia/reperfusion (I/R) …

The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …

The testis is an important male reproductive organ, which ensures reproductive function via
the secretion of testosterone and the generation of spermatozoa. Testis development begins …

Background: Despite considerable advances in pharmacotherapy, more effective
therapeutic interventions for aging-related neurodegenerative disorders (NDs), such as …

Public interest in complementary and alternative medicine has been increased worldwide,
due to its wide applications in cancer prevention and treatment. Cordycepin is one of the …

Pancreatic cancer is one of the most malignant tumors of the digestive tract, with the poor
prognosis and low 5-year survival rate less than 10%. Although surgical resection and …

Abnormal lipid/lipoprotein metabolism induced by obesity may affect spermatogenesis by
inhibiting testosterone synthesis in Leydig cells. It is crucial to determine which components …

Background: Cordycepin is a nucleotide analogue from Cordyceps mushrooms, which
occupies a notable place in traditional medicine. Objective: In this review article, we have …