Cells respond to viral infections through sensors that detect non-self-molecules, and through
effectors, which can have direct antiviral activities or adapt cell physiology to limit viral …

Bunyaviruses represent the largest group of RNA viruses and are the causative agent of a
variety of febrile and hemorrhagic illnesses. Originally characterized as a single serotype in …

Various stressors such as viral infection lead to the suppression of cap-dependent
translation and the activation of the integrated stress response (ISR), since the stress …

Protein translation is a tightly regulated cellular process that is essential for gene expression
and protein synthesis. The deregulation of this process is increasingly recognized as a …

Control of protein synthesis (mRNA translation) plays key roles in sha** the proteome and
in many physiological, including homeostatic, responses. One long-known translational …

With their categorical requirement for host ribosomes to translate mRNA, viruses provide a
wealth of genetically tractable models to investigate how gene expression is remodeled post …

Highlights•The integrated stress response (ISR) is an adaptive pathway activated by various
stressors, including virus infection.•ISR activation culminates in translation arrest through …

Wuxiang virus (WUXV) is a newly discovered Bunyavirales transmitted by sandflies. It is
found to infect humans and chickens and can cause neurological symptoms and even death …

Leishmania donovani, an intracellular protozoan parasite, is the causative agent of visceral
leishmaniasis, the most severe form of leishmaniasis in humans. It is becoming increasingly …

Understanding what influences the ability of some arthropods to harbor and transmit
pathogens may be key for controlling the spread of vector-borne diseases. Arthropod …