GDF15, an emerging key player in human aging
Abstract Growth differentiation factor 15 (GDF15) is recently emerging not only as a stress-
related mitokine, but also as a key player in the aging process, being one of the most up …
related mitokine, but also as a key player in the aging process, being one of the most up …
Phylogenetics is the new genetics (for most of biodiversity)
Despite substantial progress in understanding the genetic basis for differences in
morphology, physiology, and behavior, many phenotypes of interest are difficult to study with …
morphology, physiology, and behavior, many phenotypes of interest are difficult to study with …
Life in deserts: The genetic basis of mammalian desert adaptation
Deserts are among the harshest environments on Earth. The multiple ages of different
deserts and their global distribution provide a unique opportunity to study repeated …
deserts and their global distribution provide a unique opportunity to study repeated …
Antagonistic pleiotropy in human disease
Between the 1930s and 1950s, scientists developed key principles of population genetics to
try and explain the aging process. Almost a century later, these aging theories, including …
try and explain the aging process. Almost a century later, these aging theories, including …
Pan-mammalian analysis of molecular constraints underlying extended lifespan
Although lifespan in mammals varies over 100-fold, the precise evolutionary mechanisms
underlying variation in longevity remain unknown. Species-specific genetic changes have …
underlying variation in longevity remain unknown. Species-specific genetic changes have …
Transcription factors evolve faster than their structural gene targets in the flavonoid pigment pathway
Dissecting the relationship between gene function and substitution rates is key to
understanding genome-wide patterns of molecular evolution. Biochemical pathways provide …
understanding genome-wide patterns of molecular evolution. Biochemical pathways provide …
The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS
Ecological flexibility, extended lifespans, and large brains have long intrigued evolutionary
biologists, and comparative genomics offers an efficient and effective tool for generating new …
biologists, and comparative genomics offers an efficient and effective tool for generating new …
Genome evolution and the future of phylogenomics of non-avian reptiles
Simple Summary As a group of organisms, non-avian reptiles, most of which are the~
11,000 species of lizards and snakes, are an extraordinarily diverse group, displaying a …
11,000 species of lizards and snakes, are an extraordinarily diverse group, displaying a …
A multibreed genome-wide association study for cattle leukocyte telomere length
Telomeres are terminal DNA regions of chromosomes that prevent chromosomal fusion and
degradation during cell division. In cattle, leukocyte telomere length (LTL) is associated with …
degradation during cell division. In cattle, leukocyte telomere length (LTL) is associated with …
Comparative genomics reveals convergent signals associated with the high metabolism and longevity in birds and bats
Y Matsuda, T Makino - Proceedings of the Royal Society …, 2024 - royalsocietypublishing.org
Birds and bats have long lifespans relative to their body size compared with non-flying
animals. However, the genomic basis associated with longer lifespan of flying species …
animals. However, the genomic basis associated with longer lifespan of flying species …