[HTML][HTML] PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up

MC Operti, A Bernhardt, S Grimm, A Engel… - International Journal of …, 2021 - Elsevier
Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …

Recent advances and applications of micromixers

CY Lee, LM Fu - Sensors and Actuators B: Chemical, 2018 - Elsevier
Micromixers are crucial components within micro biomedical systems. This article presents a
comprehensive review of the main state-of-the art applications of micromixers in biomedical …

A review on microfluidic-assisted nanoparticle synthesis, and their applications using multiscale simulation methods

A Agha, W Waheed, I Stiharu, V Nerguizian… - Discover Nano, 2023 - Springer
Recent years have witnessed an increased interest in the development of nanoparticles
(NPs) owing to their potential use in a wide variety of biomedical applications, including drug …

Microfluidic synthesis control technology and its application in drug delivery, bioimaging, biosensing, environmental analysis and cell analysis

CT Kung, H Gao, CY Lee, YN Wang, W Dong… - Chemical Engineering …, 2020 - Elsevier
Nanomaterials have attracted significant attention in biomedical and environmental science
in recent years due to their unique thermal, optical, electrical and magnetic properties. The …

Synthesis and surface engineering of inorganic nanomaterials based on microfluidic technology

J Shen, M Shafiq, M Ma, H Chen - Nanomaterials, 2020 - mdpi.com
The controlled synthesis and surface engineering of inorganic nanomaterials hold great
promise for the design of functional nanoparticles for a variety of applications, such as drug …

Toward continuous production of high-quality nanomaterials using microfluidics: Nanoengineering the shape, structure and chemical composition

V Sebastian - Nanoscale, 2022 - pubs.rsc.org
Over the last decade, a multitude of synthesis strategies has been reported for the
production of high-quality nanoparticles. Wet-chemical methods are generally the most …

Microfluidics for silica biomaterials synthesis: Opportunities and challenges

N Hao, Y Nie, JXJ Zhang - Biomaterials science, 2019 - pubs.rsc.org
The rational design and controllable synthesis of silica nanomaterials bearing unique
physicochemical properties is becoming increasingly important for a variety of biomedical …

Yeast cell membrane-camouflaged PLGA nanoparticle platform for enhanced cancer therapy

Y He, QW Chen, JX Yu, SY Qin, WL Liu, YH Ma… - Journal of Controlled …, 2023 - Elsevier
Temozolomide (TMZ) is an oral DNA-alkylating drug used in colorectal cancer (CRC)
chemotherapy. In this work, we proposed a safe and biomimetic platform for macrophages …

Nanoengineering palladium plasmonic nanosheets inside polymer nanospheres for photothermal therapy and targeted drug delivery

L Uson, C Yus, G Mendoza, E Leroy… - Advanced Functional …, 2022 - Wiley Online Library
The incorporation of plasmonic nanoconstructs in biodegradable polymeric nanoparticles
(NPs), together with therapeutic drugs in a controlled procedure is of interest for different …

Encapsulation of large-size plasmids in PLGA nanoparticles for gene editing: comparison of three different synthesis methods

T López-Royo, V Sebastián, L Moreno-Martínez… - Nanomaterials, 2021 - mdpi.com
The development of new gene-editing technologies has fostered the need for efficient and
safe vectors capable of encapsulating large nucleic acids. In this work we evaluate the …