[HTML][HTML] Brain edema formation and therapy after intracerebral hemorrhage
Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of
America causing a high degree of disability and mortality. There is initial (primary) brain …
America causing a high degree of disability and mortality. There is initial (primary) brain …
Mechanisms of brain injury after intracerebral haemorrhage
The past decade has resulted in a rapid increase in knowledge of mechanisms underlying
brain injury induced by intracerebral haemorrhage (ICH). Animal studies have suggested …
brain injury induced by intracerebral haemorrhage (ICH). Animal studies have suggested …
Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS-and/or NF-κB-mediated NLRP3 inflammasome …
J Zeng, Y Chen, R Ding, L Feng, Z Fu, S Yang… - Journal of …, 2017 - Springer
Background Intracerebral hemorrhage (ICH) induces potently oxidative stress responses
and inflammatory processes. Isoliquiritigenin (ILG) is a flavonoid with a chalcone structure …
and inflammatory processes. Isoliquiritigenin (ILG) is a flavonoid with a chalcone structure …
Neuroinflammation after intracerebral hemorrhage
E Mracsko, R Veltkamp - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …
no specific treatment has been established yet. Although preclinical models of ICH have …
Preclinical and clinical research on inflammation after intracerebral hemorrhage
J Wang - Progress in neurobiology, 2010 - Elsevier
Intracerebral hemorrhage (ICH) is one of the most lethal stroke subtypes. Despite the high
morbidity and mortality associated with ICH, its pathophysiology has not been investigated …
morbidity and mortality associated with ICH, its pathophysiology has not been investigated …
Inflammation after intracerebral hemorrhage
J Wang, S Doré - Journal of Cerebral Blood Flow & …, 2007 - journals.sagepub.com
Intracerebral hemorrhage (ICH) is a devastating clinical event without effective therapies.
Increasing evidence suggests that inflammatory mechanisms are involved in the …
Increasing evidence suggests that inflammatory mechanisms are involved in the …
Matrix metalloproteinases as therapeutic targets for stroke
Matrix metalloproteinases (MMPs) are important in injury and recovery in ischemic injury.
They are proteolytic enzymes that degrade all components of the extracellular matrix (ECM) …
They are proteolytic enzymes that degrade all components of the extracellular matrix (ECM) …
Involvement of ROS in BBB dysfunction
The blood–brain barrier (BBB) forms a protective barrier around the brain, with the important
function of maintaining brain homeostasis. Pathways thought to initiate BBB dysfunction …
function of maintaining brain homeostasis. Pathways thought to initiate BBB dysfunction …
Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities
The prognosis of intracerebral haemorrhage continues to be devastating despite much
research into this condition. A prominent feature of intracerebral haemorrhage is …
research into this condition. A prominent feature of intracerebral haemorrhage is …
Behavioral tests after intracerebral hemorrhage in the rat
Background and Purpose—In humans, intracerebral hemorrhage (ICH) causes marked
perihematomal edema formation and neurological deficits. A rat ICH model, involving …
perihematomal edema formation and neurological deficits. A rat ICH model, involving …