Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …

Lornoxicam (LRX) is a potent nonsteroidal anti-inflammatory drug (NSAID) used extensively
to manage pain and inflammatory conditions. However, the drug possesses poor aqueous …

Abstract Quality-by-design (QbD) approach has been applied to optimize lipid-based
nanosystems formulations, including solid lipid nanoparticles (SLN), nanostructured lipid …

Solid lipid nanoparticles (SLNs) are one of the developed technologies for addressing the
bioavailability and targeting issues of drug delivery. In this review article, we attempted to …

The solid lipid nanoparticles (SLNs) usually consists of active drug molecules along with
solid lipids, surfactants, and/or co-surfactants. They possess some potential features such as …

The objective of current study was to develop solid lipid nanoparticles-loaded with
simvastatin (SIM-SLNs) and investigate their in vivo anti-hyperlipidemic activity in poloxamer …

Background Carvedilol, the anti-hypertensive drug, has poor bioavailability when
administered orally. Ethosomes-mediated transdermal delivery is considered a potential …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …