Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …

Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …

Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

ABSTRACT BACKGROUND AND PURPOSE Recently, there has been growing interest in
the glymphatic system (the functional waste clearance pathway for the central nervous …

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of
various cerebrovascular diseases. In this work, we put forth a physics-informed deep …

The paravascular pathway, also known as the “glymphatic” pathway, is a recently described
system for waste clearance in the brain. According to this model, cerebrospinal fluid (CSF) …

Background: Cerebrovascular disease is a common comorbidity in patients with Alzheimer's
disease (AD). It is believed to contribute additively to the cognitive impairment and to lower …

Background and Purpose—Cerebral small vessel disease (SVD) is a major cause of stroke
and dementia, but underlying disease mechanisms are still largely unknown, partly because …

Background: The incidence of dementia is projected to rise over the coming decades, but
with no sensitive diagnostic tests available. Vascular pathology precedes the deposition of …