Growth hormone, insulin-like growth factors, and the skeleton

A Giustina, G Mazziotti, E Canalis - Endocrine reviews, 2008 - academic.oup.com
Abstract GH and IGF-I are important regulators of bone homeostasis and are central to the
achievement of normal longitudinal bone growth and bone mass. Although GH may act …

The role of leptin in regulating bone metabolism

J Upadhyay, OM Farr, CS Mantzoros - Metabolism, 2015 - Elsevier
Leptin was initially best known for its role in energy homeostasis and regulation of energy
expenditure. In the past few years we have realized that leptin also plays a major role in …

Functional hypothalamic amenorrhea: an endocrine society clinical practice guideline

CM Gordon, KE Ackerman, SL Berga… - The Journal of …, 2017 - academic.oup.com
Abstract Cosponsoring Associations: The American Society for Reproductive Medicine, the
European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was …

Dose‐response relationships between energy availability and bone turnover in young exercising women

R Ihle, AB Loucks - Journal of bone and mineral research, 2004 - academic.oup.com
To help refine nutritional guidelines for military servicewomen, we assessed bone turnover
after manipulating the energy availability of 29 young women. Bone formation was impaired …

[HTML][HTML] Leptin and reproduction: a review

S Moschos, JL Chan, CS Mantzoros - Fertility and sterility, 2002 - Elsevier
Objective: To review recent advances in understanding the role of leptin in the physiology
and pathophysiology of reproduction, with a focus on relevant clinical situations. Design: A …

Hypothalamic amenorrhea and the long-term health consequences

CL Shufelt, T Torbati, E Dutra - Seminars in reproductive …, 2017 - thieme-connect.com
The menstrual cycle is a reproductive vital sign and provides insight into hormonal
imbalance as well as pregnancy. The significance of estrogen, however, extends beyond …

Increased bone marrow fat in anorexia nervosa

MA Bredella, PK Fazeli, KK Miller… - The Journal of …, 2009 - academic.oup.com
Context: Although women with anorexia nervosa (AN) have severe depletion of body fat, a
paradoxical increase in bone marrow fat has been described. Recent data suggest that …

Medical findings in outpatients with anorexia nervosa

KK Miller, SK Grinspoon, J Ciampa, J Hier… - Archives of internal …, 2005 - jamanetwork.com
Background Approximately 0.5% to 1% of college-aged women have anorexia nervosa and
most of them live in the community. However, few clinical data exist regarding community …

Leptin is an effective treatment for hypothalamic amenorrhea

SH Chou, JP Chamberland, X Liu… - Proceedings of the …, 2011 - National Acad Sciences
Hypothalamic amenorrhea (HA) is associated with dysfunction of the hypothalamic-pituitary-
peripheral endocrine axes, leading to infertility and bone loss, and usually is caused by …

Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa

S Grinspoon, E Thomas, S Pitts, E Gross… - Annals of internal …, 2000 - acpjournals.org
Background: Anorexia nervosa is highly prevalent among young women. Objective: To
determine prevalence and predictive factors for regional bone loss. Design: Prospective …