Statistical tests for differential expression in cDNA microarray experiments

X Cui, GA Churchill - Genome biology, 2003 - Springer
Extracting biological information from microarray data requires appropriate statistical
methods. The simplest statistical method for detecting differential expression is the t test …

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

K Mirnics, FA Middleton, DA Lewis, P Levitt - Trends in neurosciences, 2001 - cell.com
The level of cellular and molecular complexity of the nervous system creates unique
problems for the neuroscientist in the design and implementation of functional genomic …

Assessing gene significance from cDNA microarray expression data via mixed models

RD Wolfinger, G Gibson, ED Wolfinger… - Journal of …, 2001 - liebertpub.com
The determination of a list of differentially expressed genes is a basic objective in many
cDNA microarray experiments. We present a statistical approach that allows direct control …

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

R Zenz, R Eferl, L Kenner, L Florin, L Hummerich… - Nature, 2005 - nature.com
Psoriasis is a frequent, inflammatory disease of skin and joints with considerable morbidity.
Here we report that in psoriatic lesions, epidermal keratinocytes have decreased expression …

Evaluation of gene expression measurements from commercial microarray platforms

PK Tan, TJ Downey, EL Spitznagel Jr, P Xu… - Nucleic acids …, 2003 - academic.oup.com
Multiple commercial microarrays for measuring genome‐wide gene expression levels are
currently available, including oligonucleotide and cDNA, single‐and two‐channel formats …

Non-invasive fetal genetic screening by digital analysis

S Quake, HMC Fan - US Patent 7,888,017, 2011 - Google Patents
The present methods are exemplified by a process in which maternal blood containing fetal
DNA is diluted to a nominal value of approximately 0.5 genome equivalent of DNA per …

Gene expression patterns in human placenta

R Sood, JL Zehnder, ML Druzin… - Proceedings of the …, 2006 - National Acad Sciences
The placenta is the principal metabolic, respiratory, excretory, and endocrine organ for the
first 9 months of fetal life. Its role in fetal and maternal physiology is remarkably diverse …

Identification of common pathways mediating differentiation of bone marrow-and adipose tissue-derived human mesenchymal stem cells into three mesenchymal …

TM Liu, M Martina, DW Hutmacher, JHP Hui… - Stem …, 2007 - academic.oup.com
Mesenchymal stem cells derived from human bone marrow (hBMSCs) and human adipose
tissue (hAMSCs) represent a useful source of progenitor cells for cell therapy and tissue …

AGEMAP: a gene expression database for aging in mice

JM Zahn, S Poosala, AB Owen, DK Ingram… - PLoS …, 2007 - journals.plos.org
We present the AGEMAP (Atlas of Gene Expression in Mouse Aging Project) gene
expression database, which is a resource that catalogs changes in gene expression as a …

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia

K Kanasaki, K Palmsten, H Sugimoto, S Ahmad… - Nature, 2008 - nature.com
Despite intense investigation, mechanisms that facilitate the emergence of the pre-
eclampsia phenotype in women are still unknown. Placental hypoxia, hypertension …