This Perspective focuses on thiol-mediated uptake, that is, the entry of substrates into cells
enabled by oligochalcogenides or mimics, often disulfides, and inhibited by thiol-reactive …

Disulfide bonds are widely found in natural peptides and play a pivotal role in stabilizing
their secondary structures, which are highly associated with their biological functions …

Fc region binding peptide conjugated with attenuated cationic amphiphilic lytic peptide L17E
trimer [FcB (L17E) 3] was designed for immunoglobulin G (IgG) delivery into cells. Particle …

Nanocarriers that deliver functional proteins to cell interiors are an attractive platform for the
intracellular delivery of intact proteins without further modification, with in vivo compatibility …

Although targeted delivery of nanoparticulate vaccines to dendritic cells (DCs) holds
tremendous potential, it still faces insufficient internalization and endosome degradation via …

A low-molecular-weight compound whose structure strikes a fine balance between
hydrophobicity and hydrophilicity may form coacervates via liquid–liquid phase separation …

Macropinocytosis is a form of endocytosis that allows massive uptake of extracellular
materials and is a promising route for intracellular delivery of biofunctional macromolecules …

Direct delivery of proteins into plants represents a promising alternative to conventional
gene delivery for probing and modulating cellular functions without the risk of random …

Thiol-mediated uptake (TMU) is an intriguing enigma in current chemistry and biology. While
the appearance of cell-penetrating activity upon attachment of cascade exchangers (CAXs) …

Conjugates of the biocompatible polysaccharide pullulan with a cell membrane
permeabilizing peptide L17E (PL-L17Es) were prepared with the aim of producing complex …