A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Deterministic lateral displacement for particle separation: a review

J McGrath, M Jimenez, H Bridle - Lab on a Chip, 2014 - pubs.rsc.org
Deterministic lateral displacement (DLD), a hydrodynamic, microfluidic technology, was first
reported by Huang et al. in 2004 to separate particles on the basis of size in continuous flow …

Micro-scale blood plasma separation: from acoustophoresis to egg-beaters

M Kersaudy-Kerhoas, E Sollier - Lab on a Chip, 2013 - pubs.rsc.org
Plasma is a rich mine of various biomarkers including proteins, metabolites and circulating
nucleic acids. The diagnostic and therapeutic potential of these analytes has been quite …

Passive blood plasma separation at the microscale: A review of design principles and microdevices

S Tripathi, YVBV Kumar, A Prabhakar… - Journal of …, 2015 - iopscience.iop.org
Blood plasma separation is vital in the field of diagnostics and health care. Due to the
inherent advantages obtained in the transition to microscale, the recent trend in these fields …

Latest developments in microfluidic cell biology and analysis systems

GB Salieb-Beugelaar, G Simone, A Arora… - Analytical …, 2010 - ACS Publications
The multidisciplinary field of micro total analysis systems (μTAS) also called “lab-on-a-chip”
has enormously expanded in the last 2 years. By cross referencing online keyword searches …

Tunable velocity-based deterministic lateral displacement for efficient separation of particles in various size ranges

A Kheirkhah Barzoki, R Dezhkam, A Shamloo - Physics of Fluids, 2023 - pubs.aip.org
Deterministic lateral displacement (DLD) is a promising method showing great potential in
achieving high-resolution separation of suspended particles based on their size, through the …

Tip** the balance of deterministic lateral displacement devices using dielectrophoresis

JP Beech, P Jönsson, JO Tegenfeldt - Lab on a Chip, 2009 - pubs.rsc.org
We report the use of dielectrophoresis (DEP) to achieve tunability, improve dynamic range
and open up for the separation of particles with regard to parameters other than …

An integrated, multiparametric flow cytometry chip using “microfluidic drifting” based three-dimensional hydrodynamic focusing

X Mao, AA Nawaz, SCS Lin, MI Lapsley, Y Zhao… - …, 2012 - pubs.aip.org
In this work, we demonstrate an integrated, single-layer, miniature flow cytometry device that
is capable of multi-parametric particle analysis. The device integrates both particle focusing …

Deterministic microfluidic ratchet

K Loutherback, J Puchalla, RH Austin, JC Sturm - Physical review letters, 2009 - APS
We present a deterministic, nonthermal ratchet where the trajectory of particles in a certain
size range is not reversible when the sign of the pressure gradient is reversed at a low …

Directional locking and the role of irreversible interactions in deterministic hydrodynamics separations in microfluidic devices

M Balvin, E Sohn, T Iracki, G Drazer, J Frechette - Physical review letters, 2009 - APS
We performed macroscopic experiments on the motion of a sphere through an array of
obstacles that highlight the deterministic nature of the lateral displacements that lead to …