Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs

DR Tompa, A Immanuel, S Srikanth… - International journal of …, 2021 - Elsevier
The infectious microscopic viruses invade living cells to reproduce themselves, and causes
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …

Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy

WD Rawlinson, SB Boppana, KB Fowler… - The Lancet Infectious …, 2017 - thelancet.com
Congenital cytomegalovirus is the most frequent, yet under-recognised, infectious cause of
newborn malformation in developed countries. Despite its clinical and public health …

Letermovir prophylaxis for cytomegalovirus in hematopoietic-cell transplantation

FM Marty, P Ljungman, RF Chemaly… - … England Journal of …, 2017 - Mass Medical Soc
Background Cytomegalovirus (CMV) infection remains a common complication after
allogeneic hematopoietic-cell transplantation. Letermovir is an antiviral drug that inhibits the …

Congenital cytomegalovirus infection burden and epidemiologic risk factors in countries with universal screening: a systematic review and meta-analysis

P Ssentongo, C Hehnly, P Birungi, MA Roach… - JAMA network …, 2021 - jamanetwork.com
Importance Congenital cytomegalovirus (cCMV) infection is the most common congenital
infection and the leading acquired cause of developmental disabilities and sensorineural …

Approved antiviral drugs over the past 50 years

E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial

K Shahar-Nissan, J Pardo, O Peled, I Krause… - The Lancet, 2020 - thelancet.com
Background Cytomegalovirus is a common congenital infection, with high morbidity after an
early primary maternal infection. No effective means exist to prevent viral transmission to the …

Congenital hearing loss

AMH Korver, RJH Smith, G Van Camp… - Nature reviews Disease …, 2017 - nature.com
Congenital hearing loss (hearing loss that is present at birth) is one of the most prevalent
chronic conditions in children. In the majority of developed countries, neonatal hearing …

Cytomegalovirus infection during pregnancy: state of the science

M Leruez-Ville, I Foulon, R Pass, Y Ville - American journal of obstetrics and …, 2020 - Elsevier
Cytomegalovirus is the most common congenital infection, affecting 0.5–2% of all live births
and the main nongenetic cause of congenital sensorineural hearing loss and neurological …

Congenital cytomegalovirus: a European expert consensus statement on diagnosis and management

SE Luck, JW Wieringa… - The Pediatric …, 2017 - journals.lww.com
Despite the significant long-term impact of cCMV infection, there is limited evidence on
which to base many treatment decisions in clinical practice. In an era of enhanced perinatal …

Congenital Cytomegalovirus infection: advances and challenges in diagnosis, prevention and treatment

C Marsico, DW Kimberlin - Italian journal of pediatrics, 2017 - Springer
Cytomegalovirus (CMV) is the most frequent cause of congenital infection worldwide, with
an estimated incidence in developed countries of 0.6–0.7% of all live births. The burden of …