Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs
The infectious microscopic viruses invade living cells to reproduce themselves, and causes
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …
Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy
WD Rawlinson, SB Boppana, KB Fowler… - The Lancet Infectious …, 2017 - thelancet.com
Congenital cytomegalovirus is the most frequent, yet under-recognised, infectious cause of
newborn malformation in developed countries. Despite its clinical and public health …
newborn malformation in developed countries. Despite its clinical and public health …
Letermovir prophylaxis for cytomegalovirus in hematopoietic-cell transplantation
Background Cytomegalovirus (CMV) infection remains a common complication after
allogeneic hematopoietic-cell transplantation. Letermovir is an antiviral drug that inhibits the …
allogeneic hematopoietic-cell transplantation. Letermovir is an antiviral drug that inhibits the …
Congenital cytomegalovirus infection burden and epidemiologic risk factors in countries with universal screening: a systematic review and meta-analysis
Importance Congenital cytomegalovirus (cCMV) infection is the most common congenital
infection and the leading acquired cause of developmental disabilities and sensorineural …
infection and the leading acquired cause of developmental disabilities and sensorineural …
Approved antiviral drugs over the past 50 years
E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial
K Shahar-Nissan, J Pardo, O Peled, I Krause… - The Lancet, 2020 - thelancet.com
Background Cytomegalovirus is a common congenital infection, with high morbidity after an
early primary maternal infection. No effective means exist to prevent viral transmission to the …
early primary maternal infection. No effective means exist to prevent viral transmission to the …
Congenital hearing loss
AMH Korver, RJH Smith, G Van Camp… - Nature reviews Disease …, 2017 - nature.com
Congenital hearing loss (hearing loss that is present at birth) is one of the most prevalent
chronic conditions in children. In the majority of developed countries, neonatal hearing …
chronic conditions in children. In the majority of developed countries, neonatal hearing …
Cytomegalovirus infection during pregnancy: state of the science
Cytomegalovirus is the most common congenital infection, affecting 0.5–2% of all live births
and the main nongenetic cause of congenital sensorineural hearing loss and neurological …
and the main nongenetic cause of congenital sensorineural hearing loss and neurological …
Congenital cytomegalovirus: a European expert consensus statement on diagnosis and management
SE Luck, JW Wieringa… - The Pediatric …, 2017 - journals.lww.com
Despite the significant long-term impact of cCMV infection, there is limited evidence on
which to base many treatment decisions in clinical practice. In an era of enhanced perinatal …
which to base many treatment decisions in clinical practice. In an era of enhanced perinatal …
Congenital Cytomegalovirus infection: advances and challenges in diagnosis, prevention and treatment
C Marsico, DW Kimberlin - Italian journal of pediatrics, 2017 - Springer
Cytomegalovirus (CMV) is the most frequent cause of congenital infection worldwide, with
an estimated incidence in developed countries of 0.6–0.7% of all live births. The burden of …
an estimated incidence in developed countries of 0.6–0.7% of all live births. The burden of …