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[HTML][HTML] Canalization and plasticity in psychopathology
This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …
model of a general factor of psychopathology. To achieve this, we have distinguished …
[HTML][HTML] More than meets the eye: The role of sensory dimensions in psychedelic brain dynamics, experience, and therapeutics
Psychedelics are undergoing a major resurgence of scientific and clinical interest. While
multiple theories and frameworks have been proposed, there is yet no universal agreement …
multiple theories and frameworks have been proposed, there is yet no universal agreement …
Psychedelics alter metaphysical beliefs
Can the use of psychedelic drugs induce lasting changes in metaphysical beliefs? While it is
popularly believed that they can, this question has never been formally tested. Here we …
popularly believed that they can, this question has never been formally tested. Here we …
Pattern breaking: a complex systems approach to psychedelic medicine
Recent research has demonstrated the potential of psychedelic therapy for mental health
care. However, the psychological experience underlying its therapeutic effects remains …
care. However, the psychological experience underlying its therapeutic effects remains …
Neural mechanisms and psychology of psychedelic ego dissolution
Neuroimaging studies of psychedelics have advanced our understanding of hierarchical
brain organization and the mechanisms underlying their subjective and therapeutic effects …
brain organization and the mechanisms underlying their subjective and therapeutic effects …
Neural mechanisms of psychedelic visual imagery
Visual alterations under classic psychedelics can include rich phenomenological accounts
of eyes-closed imagery. Preclinical evidence suggests agonism of the 5-HT2A receptor may …
of eyes-closed imagery. Preclinical evidence suggests agonism of the 5-HT2A receptor may …
Psychedelics as potential catalysts of scientific creativity and insight
Creativity, that is the creation of ideas or objects considered both novel and valuable, is
among the most important and highly valued of human traits, and a fundamental aspect of …
among the most important and highly valued of human traits, and a fundamental aspect of …
Integrated world modeling theory expanded: Implications for the future of consciousness
Integrated world modeling theory (IWMT) is a synthetic theory of consciousness that uses the
free energy principle and active inference (FEP-AI) framework to combine insights from …
free energy principle and active inference (FEP-AI) framework to combine insights from …
Forgetting ourselves in flow: an active inference account of flow states and how we experience ourselves within them
Flow has been described as a state of optimal performance, experienced universally across
a broad range of domains: from art to athletics, gaming to writing. However, its phenomenal …
a broad range of domains: from art to athletics, gaming to writing. However, its phenomenal …
From relaxed beliefs under psychedelics (REBUS) to revised beliefs after psychedelics (REBAS)
Abstract The Relaxed Beliefs Under pSychedelics (REBUS) model proposes that
serotonergic psychedelics decrease the precision weighting of neurobiologically-encoded …
serotonergic psychedelics decrease the precision weighting of neurobiologically-encoded …