Polyvalent interactions in biological systems: implications for design and use of multivalent ligands and inhibitors
Found throughout biology, polyvalent interactions are characterized by the simultaneous
binding of multiple ligands on one biological entity to multiple receptors on another (top part …
binding of multiple ligands on one biological entity to multiple receptors on another (top part …
Dendrimers in biomedical applications—reflections on the field
S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …
interest in certain medical applications such as drug delivery, gene transfection, and …
Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren
Überall in der Biologie kommen polyvalente Wechselwirkungen vor. Sie zeichnen sich
durch die gleichzeitige Bindung mehrerer Liganden einer biologischen Einheit an mehrere …
durch die gleichzeitige Bindung mehrerer Liganden einer biologischen Einheit an mehrere …
The cluster glycoside effect
JJ Lundquist, EJ Toone - Chemical reviews, 2002 - ACS Publications
Myriad biological communication events achieve the requisite level of specificity by
exploiting the rich structural and functional diversity of glycoconjugates. Although a wide …
exploiting the rich structural and functional diversity of glycoconjugates. Although a wide …
Glycopolymer nanobiotechnology
Molecular recognition plays an important role in living systems. 1, 2 Representative
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …
Polymer therapeutics: concepts and applications
R Haag, F Kratz - Angewandte Chemie International Edition, 2006 - Wiley Online Library
Polymer therapeutics encompass polymer–protein conjugates, drug–polymer conjugates,
and supramolecular drug‐delivery systems. Numerous polymer–protein conjugates with …
and supramolecular drug‐delivery systems. Numerous polymer–protein conjugates with …
Functional dendrimers, hyperbranched and star polymers
K Inoue - Progress in polymer science, 2000 - Elsevier
Over the past decade, a number of excellent reviews on hyperbranched polymers and
dendrimers have been published covering the topics from details to highlights and …
dendrimers have been published covering the topics from details to highlights and …
Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to …
The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …
Dendrimers: from design to application—a progress report
M Fischer, F Vögtle - Angewandte Chemie International Edition, 1999 - Wiley Online Library
A unique combination of a clearly defined particle structure and a very highly functionalized
surface is offered by the topical dendrimers. Many groups work on this unusual molecular …
surface is offered by the topical dendrimers. Many groups work on this unusual molecular …
Dendritic polymers in biomedical applications: from potential to clinical use in diagnostics and therapy
Dendrimers are characterized by a combination of high end‐group functionality and a
compact, precisely defined molecular structure. These characteristics can be used in …
compact, precisely defined molecular structure. These characteristics can be used in …