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Therapeutic siRNA: state of the art
ABSTRACT RNA interference (RNAi) is an ancient biological mechanism used to defend
against external invasion. It theoretically can silence any disease-related genes in a …
against external invasion. It theoretically can silence any disease-related genes in a …
The challenge and prospect of mRNA therapeutics landscape
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …
in the pharmaceutical industry because they can be used for precise and individualized …
Polycaprolactone and its derivatives for drug delivery
R Pawar, A Pathan, S Nagaraj… - Polymers for …, 2023 - Wiley Online Library
Polycaprolactone (PCL) is polymer of 21st centuries. PCL is a biodegradable and
biocompatible polymer used for various healthcare applications. This review explores the …
biocompatible polymer used for various healthcare applications. This review explores the …
RNAi therapeutic and its innovative biotechnological evolution
Y Weng, H ** RES and endosome: challenges for siRNA delivery for cancer therapy
Small interfering RNAs (siRNAs) technology has emerged as a promising potential
treatment for viral, genetic diseases and cancers. Despite the powerful therapeutic potential …
treatment for viral, genetic diseases and cancers. Despite the powerful therapeutic potential …
Micellization of synthetic and polysaccharides-based graft copolymers in aqueous media
LI Atanase, J Desbrieres, G Riess - Progress in Polymer Science, 2017 - Elsevier
This review highlights recent advances in the micellization of synthetic graft copolymers and
those based on natural precursors, particularly polysaccharides. Synthesis and …
those based on natural precursors, particularly polysaccharides. Synthesis and …
[PDF][PDF] A peptide‐network weaved nanoplatform with tumor microenvironment responsiveness and deep tissue penetration capability for cancer therapy
Targeted drug-delivery systems have been widely used to transport drugs or
macromolecules to tumor vasculature or tumor cells.[19] However, most targeted drug …
macromolecules to tumor vasculature or tumor cells.[19] However, most targeted drug …
Strategies for improving the payload of small molecular drugs in polymeric micelles
Y Zhang, T Ren, J Gou, L Zhang, X Tao, B Tian… - Journal of Controlled …, 2017 - Elsevier
In the past few years, substantial efforts have been made in the design and preparation of
polymeric micelles as novel drug delivery vehicles. Typically, polymeric micelles possess a …
polymeric micelles as novel drug delivery vehicles. Typically, polymeric micelles possess a …