African genetic diversity: implications for human demographic history, modern human origins, and complex disease map**
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …
important for reconstructing human evolutionary history and for understanding the genetic …
Innate Immune Recognition of Mycobacterium tuberculosis
J Kleinnijenhuis, M Oosting… - Journal of …, 2011 - Wiley Online Library
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem,
with 10 million new cases diagnosed each year. Innate immunity plays an important role in …
with 10 million new cases diagnosed each year. Innate immunity plays an important role in …
Innate immune gene polymorphisms in tuberculosis
Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …
infectious agent. Recent studies targeting candidate genes and “case-control” association …
Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host–pathogen interaction
Approximately one third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …
Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis
The evidence for a human genetic component in susceptibility to tuberculosis (TB) is
incontrovertible. Quite apart from studies of rare disease events illustrating the importance of …
incontrovertible. Quite apart from studies of rare disease events illustrating the importance of …
Sensing of Mycobacterium tuberculosis and consequences to both host and bacillus
CE Stamm, AC Collins, MU Shiloh - Immunological reviews, 2015 - Wiley Online Library
Mycobacterium tuberculosis (Mtb), the primary causative agent of human tuberculosis, has
killed more people than any other bacterial pathogen in human history and remains one of …
killed more people than any other bacterial pathogen in human history and remains one of …
Influence of genetic polymorphism towards pulmonary tuberculosis susceptibility
Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …
control, candidate-gene, family studies and genome-wide association studies (GWAS) …
Receptor‐mediated recognition of mycobacterial pathogens
Mycobacteria are a genus of bacteria that range from the non‐pathogenic M ycobacterium
smegmatis to M ycobacterium tuberculosis, the causative agent of tuberculosis in humans …
smegmatis to M ycobacterium tuberculosis, the causative agent of tuberculosis in humans …
Dectin-1 and DC-SIGN polymorphisms associated with invasive pulmonary Aspergillosis infection
J Sainz, CB Lupiáñez, J Segura-Catena, L Vazquez… - PloS one, 2012 - journals.plos.org
The recognition of pathogen-derived structures by C-type lectins and the chemotactic activity
mediated by the CCL2/CCR2 axis are critical steps in determining the host immune …
mediated by the CCL2/CCR2 axis are critical steps in determining the host immune …
Innate signaling by the C-type lectin DC-SIGN dictates immune responses
Effective immune responses depend on the recognition of pathogens by dendritic cells
(DCs) through pattern recognition receptors (PRRs). These receptors induce specific …
(DCs) through pattern recognition receptors (PRRs). These receptors induce specific …