Perspectives on cancer therapy‐induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients

ST Sonis, LS Elting, D Keefe… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND A frequent complication of anticancer treatment, oral and gastrointestinal
(GI) mucositis, threatens the effectiveness of therapy because it leads to dose reductions …

Primary brain tumours in adults

A Behin, K Hoang-Xuan, AF Carpentier, JY Delattre - The Lancet, 2003 - thelancet.com
The most frequent primary brain tumours in adults are gliomas and primary CNS
lymphomas. In gliomas, molecular genetic analysis plays an increasing part in classification …

High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial

AJM Ferreri, M Reni, M Foppoli, M Martelli… - The Lancet, 2009 - thelancet.com
Background Chemotherapy with high-dose methotrexate is the conventional approach to
treat primary CNS lymphomas, but superiority of polychemotherapy compared with high …

High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial

E Thiel, A Korfel, P Martus, L Kanz, F Griesinger… - The lancet …, 2010 - thelancet.com
Background High-dose methotrexate is the standard of care for patients with newly
diagnosed primary CNS lymphoma. The role of whole brain radiotherapy is controversial …

Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96–07

T Batchelor, K Carson, A O'Neill… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: A multicenter, phase II study of single-agent, intravenous methotrexate in newly
diagnosed non-AIDS-related primary CNS lymphoma was conducted in the New …

Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy

H Pels, IGH Schmidt-Wolf, A Glasmacher… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: To evaluate response rate, response duration, overall survival (OS), and toxicity in
primary CNS lymphoma (PCNSL) after systemic and intraventricular chemotherapy with …

A multicenter study of treatment of primary CNS lymphoma

AJM Ferreri, M Reni, F Pasini, A Calderoni, U Tirelli… - Neurology, 2002 - AAN Enterprises
Objective: To characterize the therapeutic variables correlated to outcome in 370 patients
with primary CNS lymphoma. Methods: Planned treatment was radiotherapy (RT) in 98 …

MRI features of primary central nervous system lymphomas at presentation

U Buhring, U Herrlinger, T Krings, R Thiex, M Weller… - Neurology, 2001 - AAN Enterprises
Pretreatment MRI examinations of 40 immunologically competent patients with primary CNS
lymphoma (PCNSL) were evaluated (24 men, 16 women, median age 63 years). Seventy …

High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma

G Illerhaus, R Marks, G Ihorst… - Journal of clinical …, 2006 - ascopubs.org
Purpose To improve survival and reduce toxicity in primary CNS lymphoma (PCNSL)
treatment, we conducted a multicenter phase II study with early high-dose chemotherapy …

Results of whole-brain radiation as salvage of methotrexate failure for immunocompetent patients with primary CNS lymphoma

PL Nguyen, A Chakravarti, DM Finkelstein… - Journal of Clinical …, 2005 - ascopubs.org
Purpose This study evaluates the efficacy and toxicity of whole-brain radiation therapy
(WBRT) as salvage therapy for immunocompetent patients who failed initial high-dose …