Early mast cell (MC) infiltration has been reported in a wide range of human and animal
tumors particularly malignant melanoma and breast and colorectal cancer. The …

Chimeric antigen receptor (CAR) T cells have demonstrated promising efficacy, particularly
in hematologic malignancies. One challenge regarding CAR T cells in solid tumors is the …

Metastasis is the primary cause of cancer patient morbidity and mortality, but due to
persisting gaps in our knowledge, it remains untreatable. Metastases often occur as patient …

The emergence of cancer immunotherapies utilizing adoptive cell transfer (ACT) continues
to be one of the most promising strategies for cancer treatment. Mast cells (MCs) which …

Introduction Neuropilin-1 (NRP1) binds to many ligands and co-receptors and affects cell
survival and migration, which is essential for tumor progression. However, there are still …

Cancer stem-like cells (CSCs) are associated with cancer progression, metastasis, and
recurrence, and may also represent a subset of circulating tumor cells (CTCs). In our prior …

Prostate cancer (PCa) is the second most common cancer type in men, and in advanced
metastatic stages is considerable incurable. This justifies the need for efficient early …

Patients diagnosed with advanced prostate cancer (PCa) often experience incurable bone
metastases; however, a lack of relevant experimental models has hampered the study of …

Chitosan, a natural polysaccharide sourced from crustaceans and insects, is often used with
hydrogels in wound care. Evaluating its cytotoxicity and antimicrobial properties is crucial for …

Background CD8+ tumor-infiltrating T lymphocytes (T-TILs) in the tumor microenvironment
(TME) play an important role in tumor development, and miRNAs regulate tumor cell …