Information exchange is essential for the brain, where it communicates the physiological and
pathological signals to the periphery and vice versa. Extracellular vesicles (EVs) are a …

Cellular prion protein (PrPC) is a glycosylphosphatidylinositol (GPI)-anchored protein most
abundantly found in the outer membrane of neurons. Due to structural characteristics (a …

Synaptic dysfunction is an early mechanism in Alzheimer's disease that involves
progressively larger areas of the brain over time. However, how it starts and propagates is …

Neuroinflammation is a hallmark of many neurological diseases including traumatic brain
injury (TBI), which is usually characterized by two pathological hallmarks: activation of …

Neuroinflammation plays a significant role in ischemic injury, which can be promoted by
oxidized mitochondrial DNA (Ox-mtDNA). Cytidine/uridine monophosphate kinase 2 …

Following ischemic stroke, brain‐resident activated microglia and peripherally infiltrated
inflammatory cells create a complicated and overactivated brain immune microenvironment …

We sought to identify alterations in the quantity of plasma brain-derived extracellular
vesicles (EV) over the first month post-stroke to shed light on related injury and repair …

Extracellular vesicles (EVs) are considered a vital component of cell-to-cell communication
and represent a new frontier in diagnostics and a means to identify pathways for therapeutic …

Microglia (MG) play a crucial role as the predominant myeloid cells in the central nervous
system and are commonly activated in multiple sclerosis. They perform essential functions …

Simple Summary A stroke occurs when there is a lack of blood flow to the brain. Stroke
injures the brain and can have devastating outcomes depending on the size and location of …