[HTML][HTML] Low dose ionizing radiation effects on the immune system

K Lumniczky, N Impens, G Armengol, S Candéias… - Environment …, 2021 - Elsevier
Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Radon exposure—therapeutic effect and cancer risk

A Maier, J Wiedemann, F Rapp, F Papenfuß… - International Journal of …, 2020 - mdpi.com
Largely unnoticed, all life on earth is constantly exposed to low levels of ionizing radiation.
Radon, an imperceptible natural occurring radioactive noble gas, contributes as the largest …

Clinically relevant radiation exposure differentially impacts forms of cell death in human cells of the innate and adaptive immune system

SE Falcke, PF Rühle, L Deloch, R Fietkau… - International journal of …, 2018 - mdpi.com
In cancer treatments, especially high-dose radiotherapy (HDRT) is applied. Patients
suffering from chronic inflammatory diseases benefit from low-dose radiation therapy …

[HTML][HTML] The influence of radiation on bone and bone cells—differential effects on osteoclasts and osteoblasts

AJ Donaubauer, L Deloch, I Becker, R Fietkau… - International journal of …, 2020 - mdpi.com
The bone is a complex organ that is dependent on a tight regulation between bone
formation by osteoblasts (OBs) and bone resorption by osteoclasts (OCs). These processes …

Organ-specific effects of low dose radiation exposure: a comprehensive review

E Shin, S Lee, H Kang, J Kim, K Kim, HS Youn… - Frontiers in …, 2020 - frontiersin.org
Ionizing radiation (IR) is a high-energy radiation whose biological effects depend on the
irradiation doses. Low-dose radiation (LDR) is delivered during medical diagnoses or by an …

A Novel Activatable Nanoradiosensitizer for Second Near‐Infrared Fluorescence Imaging‐Guided Safe‐Dose Synergetic Chemo‐Radiotherapy of Rheumatoid …

Y **, D Li, X Zheng, M Gao, W Wang… - Advanced …, 2024 - Wiley Online Library
The precise theranostics of rheumatoid arthritis (RA) remains a formidable challenge in
clinical practice. Exploring novel applications of contemporary therapeutic approaches like …

The use of low-dose radiation therapy in osteoarthritis: a review

APH Dove, A Cmelak, K Darrow, KN McComas… - International Journal of …, 2022 - Elsevier
Despite its clinical use and investigation in other countries, low dose radiation therapy
(LDRT) in the treatment of osteoarthritis (OA) is minimally used in the United States (US) …

[HTML][HTML] Role of low-dose radiation in senescence and aging: A beneficial perspective

J Xu, D Liu, D Zhao, X Jiang, X Meng, L Jiang, M Yu… - Life Sciences, 2022 - Elsevier
Cellular senescence refers to the permanent arrest of cell cycle caused by intrinsic and/or
extrinsic stressors including oncogene activation, irradiation, DNA damage, oxidative stress …

Chrysin encapsulated copper nanoparticles with low dose of gamma radiation elicit tumor cell death through p38 MAPK/NF-κB pathways

LO Abdelhakm, EI Kandil, SZ Mansour… - … Trace Element Research, 2023 - Springer
Improving radiation effect on tumor cells using radiosensitizers is gaining traction for
improving chemoradiotherapy. This study aimed to evaluate copper nanoparticles (CuNPs) …

Low‐dose irradiation differentially impacts macrophage phenotype in dependence of fibroblast‐like synoviocytes and radiation dose

L Deloch, J Fuchs, M Rückert, R Fietkau… - Journal of …, 2019 - Wiley Online Library
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose main hallmark is
inflammation and destruction of the joints. Two cell types within the synovium that play an …