[HTML][HTML] The relationship between inflammation, impaired glymphatic system, and neurodegenerative disorders: a vicious cycle

Y Cai, Y Zhang, S Leng, Y Ma, Q Jiang, Q Wen… - Neurobiology of …, 2024 - Elsevier
The term “glymphatic” emerged roughly a decade ago, marking a pivotal point in
neuroscience research. The glymphatic system, a glial-dependent perivascular network …

Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements

AM Wright, YC Wu, L Feng, Q Wen - NMR in Biomedicine, 2024 - Wiley Online Library
Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain,
requiring its circulation throughout various brain pathways, including the ventricular system …

Glymphatic clearance estimated using diffusion tensor imaging along perivascular spaces is reduced after traumatic brain injury and correlates with plasma …

T Butler, L Zhou, I Ozsahin, XH Wang… - Brain …, 2023 - academic.oup.com
The glymphatic system is a perivascular fluid clearance system, most active during sleep,
considered important for clearing the brain of waste products and toxins. Glymphatic failure …

Cross-vendor test-retest validation of diffusion tensor image analysis along the perivascular space (DTI-ALPS) for evaluating glymphatic system function

X Liu, G Barisano, X Shao, K Jann… - Aging and …, 2024 - pmc.ncbi.nlm.nih.gov
The diffusion tensor image analysis along the perivascular space (DTI-ALPS) method was
proposed to evaluate glymphatic system (GS) function. However, few studies have validated …

Anti‐seizure medication response and the glymphatic system in patients with focal epilepsy

ST Kim, SE Kim, DA Lee, HJ Lee… - European Journal of …, 2024 - Wiley Online Library
Background and purpose We aimed to evaluate (i) glymphatic system function in patients
with focal epilepsy in comparison with healthy controls, and (ii) the association between anti …

Cellular senescence as a key contributor to secondary neurodegeneration in traumatic brain injury and stroke

Z Huang, P Xu, DC Hess, Q Zhang - Translational Neurodegeneration, 2024 - Springer
Traumatic brain injury (TBI) and stroke pose major health challenges, impacting millions of
individuals globally. Once considered solely acute events, these neurological conditions are …

Associations of MRI‐derived glymphatic system impairment with global white matter damage and cognitive impairment in mild traumatic brain injury: a DTI‐ALPS study

DX Yang, Z Sun, MM Yu, QQ Zou, PY Li… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Assessing the glymphatic function using diffusion tensor image analysis along
the perivascular space (DTI‐ALPS) may be helpful for mild traumatic brain injury (mTBI) …

Increased glymphatic system activity in patients with mild traumatic brain injury

Z Dai, Z Yang, Z Li, M Li, H Sun, Z Zhuang… - Frontiers in …, 2023 - frontiersin.org
Purpose This study aims to investigate the glymphatic system activity changes in patients
with mild traumatic brain injury (mTBI), particularly in MRI-negative patients, using analysis …

The glymphatic system for neurosurgeons: a sco** review

M Al Masri, A Corell, I Michaëlsson, AS Jakola… - Neurosurgical …, 2024 - Springer
The discovery of the glymphatic system has revolutionized our understanding of
cerebrospinal fluid (CSF) circulation and interstitial waste clearance in the brain. This …

The glymphatic system and Amyotrophic lateral sclerosis

A Eisen, M Nedergaard, E Gray, MC Kiernan - Progress in Neurobiology, 2024 - Elsevier
The glymphatic system and the meningeal lymphatic vessels provide a pathway for transport
of solutes and clearance of toxic material from the brain. Of specific relevance to ALS, this is …