Stress, depression and cardiovascular dysregulation: a review of neurobiological mechanisms and the integration of research from preclinical disease models

AJ Grippo, AK Johnson - Stress, 2009 - Taylor & Francis
Bidirectional associations between mood disorders and cardiovascular diseases are
extensively documented. However, the precise physiological and biochemical mechanisms …

The role of the innate immune system in psychiatric disorders

KA Jones, C Thomsen - Molecular and Cellular Neuroscience, 2013 - Elsevier
There is by now substantial clinical evidence for an association between specific mood
disorders and altered immune function. More recently, a number of hypotheses have been …

[HTML][HTML] Chronic stress impacts the cardiovascular system: animal models and clinical outcomes

S Golbidi, JC Frisbee, I Laher - American Journal of …, 2015 - journals.physiology.org
Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …

Angiotensin II AT1 receptor blockers as treatments for inflammatory brain disorders

JM Saavedra - Clinical science, 2012 - portlandpress.com
The effects of brain AngII (angiotensin II) depend on AT1 receptor (AngII type 1 receptor)
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …

Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: therapeutic implications

JM Saavedra, E Sánchez-Lemus, J Benicky - Psychoneuroendocrinology, 2011 - Elsevier
Poor adaptation to stress, alterations in cerebrovascular function and excessive brain
inflammation play critical roles in the pathophysiology of many psychiatric and neurological …

Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure

N Frasure-Smith, F Lespérance, M Habra, M Talajic… - Circulation, 2009 - Am Heart Assoc
Background—Depression predicts prognosis in many cardiac conditions, including
congestive heart failure (CHF). Despite heightened cardiac risk in patients with comorbid …

Heart rate variability in bipolar mania and schizophrenia

BL Henry, A Minassian, MP Paulus, MA Geyer… - Journal of psychiatric …, 2010 - Elsevier
BACKGROUND: Autonomic nervous system (ANS) dysfunction and reduced heart rate
variability (HRV) have been reported in a wide variety of psychiatric disorders, but have not …

Autonomic and inflammatory consequences of posttraumatic stress disorder and the link to cardiovascular disease

C Brudey, J Park, J Wiaderkiewicz… - American Journal …, 2015 - journals.physiology.org
Stress-and anxiety-related disorders are on the rise in both military and general populations.
Over the next decade, it is predicted that treatment of these conditions, in particular …

Depression and cardiovascular comorbidity

AH Glassman - Dialogues in clinical neuroscience, 2007 - Taylor & Francis
Depression has long had a popular link to cardiovascular disease and death. However, only
during the last 15 years has scientific evidence supporting this common wisdom been …

Novelty-seeking behavior predicts vulnerability in a rodent model of depression

KA Stedenfeld, SM Clinton, IA Kerman, H Akil… - Physiology & …, 2011 - Elsevier
BACKGROUND: The onset of major depressive disorder is likely precipitated by a
combination of heredity and life stress. The present study tested the hypothesis that rats …