N-Heterocyclic carbenes (NHC) are nowadays ubiquitous and indispensable in many
research fields, and it is not possible to imagine modern transition metal and main group …

The main contributions in the field of first-row transition-metal-catalyzed (base-metal-
catalyzed) carbonylative transformations have been summarized and discussed. The …

Complex molecular architectures containing cyclopropanes present significant challenges
for any synthetic chemist. This review aims to highlight the strategic considerations for …

The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …

Palladium-catalyzed cascade cyclizations (PCCs) are powerful synthetic tools that enable
rapid assembly of polycyclic scaffolds. Palladium complexes can promote a variety of carbon …

First-row transition-metal-mediated reactions constitute an important and growing area of
research due to the low cost, low toxicity, and exceptional synthetic versatility of these …

Natural products containing eight-membered carbocycles constitute a class of structurally
intriguing and biologically important molecules such as the famous diterpenes taxol and …

Activated cyclopropanes show versatile reactivity and are therefore powerful building blocks
in organic chemistry and natural product synthesis. This review focuses on recent …

The advent of organic synthesis and the understanding of the molecule as they occurred in
the nineteenth century and were refined in the twentieth century constitute two of the most …

Carbon monoxide is a cheap and abundant C1 building block that can be readily
incorporated into organic molecules to rapidly build structural complexity. In this Perspective …