The remarkable complexity of globular protein structures was first revealed about half a
century ago, when the crystal structure of myoglobin was determined at 2.4 Å. 1 In the …

The principal secondary structural motifs adopted by peptides assembled from β‐amino acid
units are discussed: the 14‐, 12‐, 10‐, 12/10‐, and 8‐helices, as well as the hairpin turn …

Selective construction of two distinct alkyl–alkyl bonds across the C= C bond of simple
unactivated olefins is a persistent challenge in organic synthesis. Transition metal-catalysed …

Energetically favorable local interactions can overcome the entropic cost of chain ordering
and cause otherwise flexible polymers to adopt regularly repeating backbone …

α, γ-and β, γ-hybrid peptides, which are composed of two different homologous amino acid
constituents in alternate order, are suggested as novel classes of peptide foldamers. On the …

The engineering of biological molecules is the fundamental concept behind the design of
complex materials with desirable functions. Over the last few decades, peptides and proteins …

Peptides have been heavily investigated for their biocompatible and bioactive properties.
Though a wide array of functionalities can be introduced by varying the amino acid …

Peptides containing β-amino acids are unique non-natural polymers known to assemble into
protein-like tertiary and quaternary structures. When composed solely of β-amino acids, the …