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Molecular networking as a drug discovery, drug metabolism, and precision medicine strategy
Molecular networking is a tandem mass spectrometry (MS/MS) data organizational
approach that has been recently introduced in the drug discovery, metabolomics, and …
approach that has been recently introduced in the drug discovery, metabolomics, and …
Dengue virus
A Murugesan, M Manoharan - Emerging and reemerging viral pathogens, 2020 - Elsevier
Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-
stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus …
stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus …
Metabolomics applied to the study of extracellular vesicles
C Williams, M Palviainen, NC Reichardt, PRM Siljander… - Metabolites, 2019 - mdpi.com
Cell-secreted extracellular vesicles (EVs) have rapidly gained prominence as sources of
biomarkers for non-invasive biopsies, owing to their ubiquity across human biofluids and …
biomarkers for non-invasive biopsies, owing to their ubiquity across human biofluids and …
[HTML][HTML] Prostate cancer-derived extracellular vesicles metabolic biomarkers: Emerging roles for diagnosis and prognosis
MA Hamed, V Wasinger, Q Wang, P Graham… - Journal of Controlled …, 2024 - Elsevier
Prostate cancer (PCa) is a global health concern, ranking as the most common cancer
among men in Western countries. Traditional diagnostic methods are invasive with adverse …
among men in Western countries. Traditional diagnostic methods are invasive with adverse …
Metabolomics: strategies to define the role of metabolism in virus infection and pathogenesis
M Manchester, A Anand - Advances in virus research, 2017 - Elsevier
Metabolomics is an analytical profiling technique for measuring and comparing large
numbers of metabolites present in biological samples. Combining high-throughput analytical …
numbers of metabolites present in biological samples. Combining high-throughput analytical …
Using the power of innate immunoprofiling to understand vaccine design, infection, and immunity
In the field of immunology, a systems biology approach is crucial to understanding the
immune response to infection and vaccination considering the complex interplay between …
immune response to infection and vaccination considering the complex interplay between …
Uncovering the Carboxylated Metabolome in Gut Microbiota–Host Co-metabolism: A Chemical Derivatization-Molecular Networking Approach
YZ Wang, YY Chen, XZ Wu, PR Bai, N An… - Analytical …, 2023 - ACS Publications
Gut microbiota–host co-metabolites serve as essential mediators of communication between
the host and gut microbiota. They provide nutrient sources for host cells and regulate gut …
the host and gut microbiota. They provide nutrient sources for host cells and regulate gut …
[HTML][HTML] Correlates of immune exacerbations in leprosy
A Geluk - Seminars in immunology, 2018 - Elsevier
Leprosy is still a considerable health threat in pockets of several low and middle income
countries worldwide where intense transmission is witnessed, and often results in …
countries worldwide where intense transmission is witnessed, and often results in …
OSBPL10, RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed Cubans
Ethnic groups can display differential genetic susceptibility to infectious diseases. The
arthropod-born viral dengue disease is one such disease, with empirical and limited genetic …
arthropod-born viral dengue disease is one such disease, with empirical and limited genetic …