The gut mycobiome (fungi) is a small but crucial component of the gut microbiome in
humans. Intestinal fungi regulate host homoeostasis, pathophysiological and physiological …

Since their discovery almost two decades ago, interleukin-17-producing CD4+ T cells (TH17
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …

Balanced immunity is pivotal for health and homeostasis. CD4+ helper T (Th) cells are
central to the balance between immune tolerance and immune rejection. Th cells adopt …

While intestinal Th17 cells are critical for maintaining tissue homeostasis, recent studies
have implicated their roles in the development of extra-intestinal autoimmune diseases …

Candidiasis is an infection caused by fungi from a Candida species, most commonly
Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on …

The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …

The gut fungal community represents an essential element of human health, yet its
functional and metabolic potential remains insufficiently elucidated, largely due to the limited …

Microbial infections are recognized by the innate immune system both to elicit immediate
defense and to generate long-lasting adaptive immunity. To detect and respond to vastly …

The harmonic coexistence of microorganisms with the human body is the result of a long
coevolutionary process that has minimized competition for nutrients and immunological …

Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …