Soon after the invention of the pulsed ruby laser by Maiman in 1960, investigators were
eager to examine the potential of pulsed laser radiation for medical applications. It was …

Photoacoustic (PA) imaging is a biomedical imaging modality that provides functional
information regarding the cellular and molecular signatures of tissue by using endogenous …

Author to whom all correspondence should be addressed; also at the Department of
Biomedical Engineering at Washington University in St. Louis, One Brookings Drive …

1.1 Propagation of continuous-wave light in tissues 3 1.1. 1 Basic principles, and major
scatterers and absorbers 3 1.1. 2 Theoretical description 11 1.1. 3 Monte Carlo simulation …

Biomedical photonics is defined as the science of harnessing light and other forms of radiant
energy to address problems in medicine and biology. The field has experienced explosive …

Obtaining absolute chromophore concentrations from photoacoustic images obtained at
multiple wavelengths is a nontrivial aspect of photoacoustic imaging but is essential for …

Optical spectroscopy, imaging, and therapy tissue phantoms must have the scattering and
absorption properties that are characteristic of human tissues, and over the past few …

Photoacoustic microscopy (PAM) is a hybrid in vivo imaging technique that acoustically
detects optical contrast via the photoacoustic effect. Unlike pure optical microscopic …

Imaging modalities play an important role in the clinical management of cancer, including
screening, diagnosis, treatment planning and therapy monitoring. Owing to increased …

Photoacoustics has been broadly studied in biomedicine, for both human and small animal
tissues. Photoacoustics uniquely combines the absorption contrast of light or radio …