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Osteoporosis pathogenesis and treatment: existing and emerging avenues
B Liang, G Burley, S Lin, YC Shi - Cellular & Molecular Biology Letters, 2022 - Springer
Osteoporotic fractures lead to increased disability and mortality in the elderly population.
With the rapid increase in the aging population around the globe, more effective treatments …
With the rapid increase in the aging population around the globe, more effective treatments …
Targeting tumor and bone microenvironment: Novel therapeutic opportunities for castration-resistant prostate cancer patients with bone metastasis
S Li, Y Kang, Y Zeng - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Despite standard hormonal therapy that targets the androgen receptor (AR) attenuates
prostate cancer (PCa) effectively in the initial stage, the tumor ultimately converts to …
prostate cancer (PCa) effectively in the initial stage, the tumor ultimately converts to …
Bone‐targeted exosomes: strategies and applications
J Wang, X Li, S Wang, J Cui, X Ren… - Advanced Healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …
social problem threatening human health. Exosomes, as natural cell products, have been …
Glucose oxidase‐instructed biomineralization of calcium‐based biomaterials for biomedical applications
In recent years, glucose oxidase (GOx) has aroused great research interest in the treatment
of diseases related to abnormal glucose metabolisms like cancer and diabetes. However, as …
of diseases related to abnormal glucose metabolisms like cancer and diabetes. However, as …
Near-infrared light control of GelMA/PMMA/PDA hydrogel with mild photothermal therapy for skull regeneration
Y Wu, X Zhang, B Tan, Y Shan, X Zhao, J Liao - Biomaterials Advances, 2022 - Elsevier
The development of bone tissue engineering indicates some new paths for bone defect
repair. Mild photothermal therapy (PTT) is flourishing as an exciting potential method for …
repair. Mild photothermal therapy (PTT) is flourishing as an exciting potential method for …
Nanoscale materials-based platforms for the treatment of bone-related diseases
Owing to the high density of bone tissue and the complex and highly hierarchical structure,
drugs used for the treatment of bone-related diseases are often not effectively concentrated …
drugs used for the treatment of bone-related diseases are often not effectively concentrated …
NIR light-assisted phototherapies for bone-related diseases and bone tissue regeneration: A systematic review
Z Wan, P Zhang, L Lv, Y Zhou - Theranostics, 2020 - pmc.ncbi.nlm.nih.gov
Recently, the rapid development of biomaterials has induced great interest in the precisely
targeted treatment of bone-related diseases, including bone cancers, infections, and …
targeted treatment of bone-related diseases, including bone cancers, infections, and …
Alendronate-functionalized hypoxia-responsive polymeric micelles for targeted therapy of bone metastatic prostate cancer
M Long, X Liu, X Huang, M Lu, X Wu, L Weng… - Journal of Controlled …, 2021 - Elsevier
Bone metastasis is one of the leading causes of cancer-related death and remains incurable
in spite of great efforts. Bone-targeted nanoparticle-based drug carriers can overcome the …
in spite of great efforts. Bone-targeted nanoparticle-based drug carriers can overcome the …
Rare earth smart nanomaterials for bone tissue engineering and implantology: Advances, challenges, and prospects
D Natarajan, Z Ye, L Wang, L Ge… - Bioengineering & …, 2022 - Wiley Online Library
Bone grafts or prosthetic implant designing for clinical application is challenging due to the
complexity of integrated physiological processes. The revolutionary advances of …
complexity of integrated physiological processes. The revolutionary advances of …
Mesenchymal stem cell-derived extracellular vesicles: a regulator and carrier for targeting bone-related diseases
J Tang, X Wang, X Lin, C Wu - Cell Death Discovery, 2024 - nature.com
The escalating threat of bone-related diseases poses a significant challenge to human
health. Mesenchymal stem cell (MSC)-derived extracellular vesicles (MSC-EVs), as inherent …
health. Mesenchymal stem cell (MSC)-derived extracellular vesicles (MSC-EVs), as inherent …