Clinicians face challenges in the timely diagnosis and management of pediatric sepsis.
Pediatric heart rate has been incorporated into early warning systems and studied as a …

Polymicrobial sepsis (after cecal ligation and puncture, CLP) causes robust complement
activation with release of C5a. Many adverse events develop thereafter and will be …

Background More than one in five patients presenting to the emergency department (ED)
with (suspected) infection or sepsis deteriorate within 72 h from admission. Surprisingly little …

Sepsis is associated with high mortality—particularly in low–middle income countries
(LMICs). Critical care management of sepsis is challenging in LMICs due to the lack of care …

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Background Sepsis is a life-threatening disease with an in-hospital mortality rate of
approximately 20%. Physicians at the emergency department (ED) have to estimate the risk …

Sepsis has emerged as a global health burden associated with multiple organ dysfunction
and 20% mortality rate in patients. Numerous clinical studies over the past two decades …

Justificativa e Objetivo: A sepse é um problema de saúde pública que gera impacto clínico e
econômico. O estudo objetiva descrever as características epidemiológicas e clínicas da …

Background Although the quick Sequential Organ Failure Assessment (qSOFA) score was
recently introduced to identify patients with suspected infection/sepsis, it has limitations as a …

Results: The increase in LF: HF ratio, reflecting sympathetic predominance, was more
pronounced in the LPS group compared to the placebo group, with the difference becoming …