Multi-omics approaches to disease

Y Hasin, M Seldin, A Lusis - Genome biology, 2017 - Springer
High-throughput technologies have revolutionized medical research. The advent of
genoty** arrays enabled large-scale genome-wide association studies and methods for …

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …

You are what you eat: diet, health and the gut microbiota

N Zmora, J Suez, E Elinav - Nature reviews Gastroenterology & …, 2019 - nature.com
Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces sha** the architecture and functionality of resident …

Every base matters: assessing small subunit rRNA primers for marine microbiomes with mock communities, time series and global field samples

AE Parada, DM Needham… - Environmental …, 2016 - Wiley Online Library
Microbial community analysis via high‐throughput sequencing of amplified 16S rRNA genes
is an essential microbiology tool. We found the popular primer pair 515F (515F‐C) and …

Antibiotics degradation by advanced oxidation process (AOPs): Recent advances in ecotoxicity and antibiotic-resistance genes induction of degradation products

S Li, Y Wu, H Zheng, H Li, Y Zheng, J Nan, J Ma… - Chemosphere, 2023 - Elsevier
Antibiotic contamination could cause serious risks of ecotoxicity and resistance gene
induction. Advanced oxidation processes (AOPs) such as Fenton, photocatalysis, activated …

Modulation of the root microbiome by plant molecules: the basis for targeted disease suppression and plant growth promotion

A Pascale, S Proietti, IS Pantelides… - Frontiers in plant …, 2020 - frontiersin.org
Plants host a mesmerizing diversity of microbes inside and around their roots, known as the
microbiome. The microbiome is composed mostly of fungi, bacteria, oomycetes, and …

An integrated semiconductor device enabling non-optical genome sequencing

JM Rothberg, W Hinz, TM Rearick, J Schultz, W Mileski… - Nature, 2011 - nature.com
The seminal importance of DNA sequencing to the life sciences, biotechnology and
medicine has driven the search for more scalable and lower-cost solutions. Here we …

The healthy microbiome—what is the definition of a healthy gut microbiome?

F Shanahan, TS Ghosh, PW O'Toole - Gastroenterology, 2021 - Elsevier
Use of microbiome-based biomarkers in diagnosis, prognosis, risk profiling, and precision
therapy requires definition of a healthy microbiome in different populations. To determine …

Ecology and exploration of the rare biosphere

MDJ Lynch, JD Neufeld - Nature Reviews Microbiology, 2015 - nature.com
The profound influence of microorganisms on human life and global biogeochemical cycles
underlines the value of studying the biogeography of microorganisms, exploring microbial …