Effect of pentoxifylline on renal function and urinary albumin excretion in patients with diabetic kidney disease: the PREDIAN trial

JF Navarro-González, C Mora-Fernández… - Journal of the …, 2015 - journals.lww.com
Diabetic kidney disease (DKD) is the leading cause of ESRD. We conducted an open-label,
prospective, randomized trial to determine whether pentoxifylline (PTF), which reduces …

Effects of pentoxifylline on inflammatory markers and blood pressure: a systematic review and meta-analysis of randomized controlled trials

D Brie, A Sahebkar, PE Penson, M Dinca… - Journal of …, 2016 - journals.lww.com
Aim: To evaluate the impact of pentoxifylline on blood pressure (BP) and plasma TNF-α, C-
reactive protein (CRP) and IL-6 through a systematic review and meta-analysis of …

Pentoxifylline for diabetic kidney disease

D Shan, HM Wu, QY Yuan, J Li… - … of systematic reviews, 2012 - cochranelibrary.com
Background Diabetic kidney disease (DKD) is associated with increased morbidity and
mortality, mostly relating to cardiovascular complications. The relevance of inflammation in …

A double‐blind placebo‐controlled study of the efficacy and safety of pentoxifylline in early chronic Peyronie's disease

MR Safarinejad, MA Asgari, SY Hosseini… - BJU …, 2010 - Wiley Online Library
Study Type–Therapy (RCT) Level of Evidence 1b OBJECTIVE To analyse the safety and
efficacy of pentoxifylline sustained‐release (PTX‐SR) treatment in patients with early chronic …

Pentoxifylline reduces the inflammatory process in diabetic rats: relationship with decreases of pro-inflammatory cytokines and inducible nitric oxide synthase

FAO Garcia, JF Rebouças, TQ Balbino… - Journal of …, 2015 - Springer
Studies suggest that inflammation is a key factor in the pathogenesis of diabetes mellitus.
Pro-inflammatory cytokines, such as IL-6 and TNF-alpha, are produced by adipose tissue in …

Ferret coronavirus-associated diseases

J Murray, M Kiupel, RK Maes - The veterinary clinics of North …, 2010 - pmc.ncbi.nlm.nih.gov
A novel coronavirus of ferrets was first described in 1993. This coronavirus caused an
enteric disease called epizootic catarrhal enteritis (ECE). Recently, a ferret systemic …

A comprehensive understanding about the pharmacological effect of diallyl disulfide other than its anti-carcinogenic activities

H He, Y Ma, H Huang, C Huang, Z Chen… - European Journal of …, 2021 - Elsevier
Diallyl disulfide (DADS), an oil-soluble sulfur compound that is responsible for the biological
effects of garlic, displays numerous biological activities, among which its anti-cancer …

Ameliorative effect of naringenin on hyperglycemia-mediated inflammation in hepatic and pancreatic tissues of Wistar rats with streptozotocin-nicotinamide-induced …

T Annadurai, PA Thomas, P Geraldine - Free radical research, 2013 - Taylor & Francis
In diabetes mellitus (DM), sustained hyperglycemia results in the generation of reactive
oxygen species, ultimately leading to increased oxidative stress and inflammation in vital …

Preventive and therapeutic anti-TNF-α therapy with pentoxifylline decreases arthritis and the associated periodontal co-morbidity in mice

CM Queiroz-Junior, RLC Bessoni, VV Costa, DG Souza… - Life Sciences, 2013 - Elsevier
Aims The association between rheumatoid arthritis (RA) and periodontal disease (PD) has
long been studied and some reports suggest that treating RA may improve the associated …

Pentoxifylline decreases serum level of adhesion molecules in atherosclerosis patients

AH Mohammadpour, H Falsoleiman… - Iranian biomedical …, 2014 - pmc.ncbi.nlm.nih.gov
Background: Inflammation is involved in development, progression, and complications of
atherosclerotic disease. Clinical studies have indicated that the level of monocyte …