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Exploring pathological link between antimicrobial and amyloid peptides
Amyloid peptides (AMYs) and antimicrobial peptides (AMPs) are considered as the two
distinct families of peptides, characterized by their unique sequences, structures, biological …
distinct families of peptides, characterized by their unique sequences, structures, biological …
A mechanistic survey of Alzheimer's disease
Alzheimer's disease (AD) is the most common, age-dependent neurodegenerative disorder.
While AD has been intensively studied from different aspects, there is no effective cure for …
While AD has been intensively studied from different aspects, there is no effective cure for …
[HTML][HTML] Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model
JJ Tang, LF Huang, JL Deng, YM Wang, C Guo… - Redox biology, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease in which oxidative stress and
neuroinflammation were demonstrated to be associated with neuronal loss and cognitive …
neuroinflammation were demonstrated to be associated with neuronal loss and cognitive …
[HTML][HTML] Antimicrobial peptides (AMPs) in the pathogenesis of Alzheimer's disease: implications for diagnosis and treatment
Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
There are two major forms of the disease: sporadic (SAD)—whose causes are not …
There are two major forms of the disease: sporadic (SAD)—whose causes are not …
SEVI inhibits Aβ amyloid aggregation by cap** the β-sheet elongation edges
Inhibiting the aggregation of amyloid peptides with endogenous peptides has broad interest
due to their intrinsically high biocompatibility and low immunogenicity. Here, we investigated …
due to their intrinsically high biocompatibility and low immunogenicity. Here, we investigated …
[HTML][HTML] Neurodegenerative microbially-shaped diseases: oxidative stress meets neuroinflammation
Inflammation and oxidative stress characterize a number of chronic conditions including
neurodegenerative diseases and aging. Inflammation is a key component of the innate …
neurodegenerative diseases and aging. Inflammation is a key component of the innate …
Spatiotemporally controlled calcitonin delivery: Long-term and targeted therapy of skeletal diseases
P Yu, Y Liu, J **e, J Li - Journal of Controlled Release, 2021 - Elsevier
Bone is a connective tissue that support the entire body and protect the internal organs.
However, there are great challenges on curing intractable skeletal diseases such as …
However, there are great challenges on curing intractable skeletal diseases such as …
Hydrophobic/hydrophilic ratio of amphiphilic helix mimetics determines the effects on islet amyloid polypeptide aggregation
Amyloid depositions of human islet amyloid polypeptides (hIAPP) are associated with type II
diabetes (T2D) impacting millions of people globally. Accordingly, strategies against hIAPP …
diabetes (T2D) impacting millions of people globally. Accordingly, strategies against hIAPP …
Interplay between Antimicrobial Peptides and Amyloid Proteins in Host Defense and Disease Modulation
The biological properties of antimicrobial peptides (AMPs) and amyloid proteins and their
cross-talks have gained increasing attention due to their potential implications in both host …
cross-talks have gained increasing attention due to their potential implications in both host …
Cross-seeding between Aβ and SEVI indicates a pathogenic link and gender difference between alzheimer diseases and AIDS
Amyloid-β (Aβ) and semen-derived enhancer of viral infection (SEVI) are considered as the
two causative proteins for central pathogenic cause of Alzheimer's disease (AD) and …
two causative proteins for central pathogenic cause of Alzheimer's disease (AD) and …