Overview on gastroretentive drug delivery systems for improving drug bioavailability

CM Lopes, C Bettencourt, A Rossi, F Buttini… - International journal of …, 2016 - Elsevier
In recent decades, many efforts have been made in order to improve drug bioavailability
after oral administration. Gastroretentive drug delivery systems are a good example; they …

Raft forming system—An upcoming approach of gastroretentive drug delivery system

VD Prajapati, GK Jani, TA Khutliwala… - Journal of controlled …, 2013 - Elsevier
In recent era various technologies have been made in research and development of
controlled release oral drug delivery system to overcome various physiological difficulties …

Controlled-release effervescent floating matrix tablets of ciprofloxacin hydrochloride: Development, optimization and in vitro–in vivo evaluation in healthy human …

MI Tadros - European journal of pharmaceutics and …, 2010 - Elsevier
Ciprofloxacin hydrochloride has a short elimination half-life, a narrow absorption window
and is mainly absorbed in proximal areas of GIT. The purpose of this study was to develop a …

Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges

P Joyce, TJ Dening, TR Meola, HB Schultz… - Advanced drug delivery …, 2019 - Elsevier
Self-emulsifying drug delivery systems (SEDDS) offer potential for overcoming the inherent
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …

[HTML][HTML] Current status of supersaturable self-emulsifying drug delivery systems

H Park, ES Ha, MS Kim - Pharmaceutics, 2020 - mdpi.com
Self-emulsifying drug delivery systems (SEDDSs) are a vital strategy to enhance the
bioavailability (BA) of formulations of poorly water-soluble compounds. However, these …

An insight on novel approaches & perspectives for gastro-retentive drug delivery systems

S Dhiman, N Philip, T Gurjeet Singh… - Current Drug …, 2023 - benthamdirect.com
The conventional oral drug delivery systems face a lot of difficulties in the gastrointestinal
tract, such as inappropriate drug release and reduction in the efficacy of the doses, which …

Advances in gastro retentive drug-delivery systems

P Prinderre, C Sauzet, C Fuxen - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: In recent years, various technological improvements have been achieved and
new concepts have been developed, in the area of controlled release solid oral dosage …

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages

D Chen, XY Xu, R Li, GA Zang, Y Zhang, MR Wang… - AAPS …, 2020 - Springer
The aim of the study is to investigate the feasibility of fabricating FDM 3D-printed gastric
floating tablets with low infill percentages and the effect of infill percentage on the properties …

Floating tablets for controlled release of ofloxacin via compression coating of hydroxypropyl cellulose combined with effervescent agent

X Qi, H Chen, Y Rui, F Yang, N Ma, Z Wu - International journal of …, 2015 - Elsevier
To prolong the residence time of dosage forms within gastrointestinal trace until all drug
released at desired rate was one of the real challenges for oral controlled-release drug …

Advanced 3D electrospinning “Xspin” System: fabrication of bifiber floating oral pharmaceutical scaffolds for controlled drug delivery

AY Darwesh, Y Zhang, NH Aghda, F Alkadi… - Molecular …, 2024 - ACS Publications
Electrospinning has become a widely used and efficient method for manufacturing
nanofibers from diverse polymers. This study introduces an advanced electrospinning …