The vascular inflammatory response involves complex interaction between inflammatory
cells (neutrophils, lymphocytes, monocytes, macrophages), endothelial cells (ECs), vascular …

Atherosclerotic plaque rupture with luminal thrombosis is the most common mechanism
responsible for the majority of acute coronary syndromes and sudden coronary death. The …

and by CD40/CD40 ligand (CD40L and CD154) interactions. 18–22 Once adherent, the
monocytes transmigrate into the tunica intima, the innermost layer of the arterial wall …

Beyond an eminent role in hemostasis and thrombosis, platelets are characterized by expert
functions in assisting and modulating inflammatory reactions and immune responses. This is …

Atherosclerosis is an inflammatory disease, characterized by the accumulation of
macrophage-derived foam cells in the vessel wall and accompanied by the production of a …

Fatty acid-binding proteins are cytosolic fatty acid chaperones, and the adipocyte isoform,
aP2, plays an important role in obesity and glucose metabolism. Recently, this protein has …

Our current understanding of the vascular biology of atherogenesis and its clinical
manifestations suggests a pathophysiology that is much more complex than mere lipid …

Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …

The transition from stable to rupture-prone and ruptured atherosclerotic plaques involves
many processes, including an altered balance between inflammation and fibrosis. An …

The pathology of cardiovascular disease (CVD) is complex; multiple biological pathways
have been implicated, including, but not limited to, inflammation and oxidative stress …